Fluorescein-r Beta-Amyloid (1-42)

Human beta-amyloid (1-42) has been covalently labeled with Fluorescein Isothiocyante and assayed for fluorescence. The FITC label has a maximum absorbance at 495 and a maximum emission at 525nm. This FITC labeled form of recombinant beta-amyloid (1-42) is ideally suited to localization experiments, aggregation monitoring, and binding kinetics without the need for mutations or further labeling. This product may be applicable to in vitro or in vivo studies monitoring aggregation, binding, or cellular uptake and trafficking ¹. The addition of the FITC allows for monitoring through microscopy of fluorescence spectroscopy ² with both live cells and lipid models. Oligomer formation, fibril formation, or other structural assembly could also be attempted ³.