RVX-208

RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo Reduces atherosclerosis.

Catalog ID: CV-1010

$133.00 – $523.00

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  • Product Details
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 370.4

  • References

    1. Picaud, S., et al., (2013) Proc. Natl. Acad. Sci. USA, 110 : 19754
    2. McLure, K.G., et al., (2013) PLoS One, 8 : e83190
    3. Bailey, D., et al., (2010) J. Am. Coll. Cardiol., 55 : 2580
    4. Jahagirdar, R., et al., (2014) Atherosclerosis, 236 : 91

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