Ascomycin
Analog of FK-506. Potent immunosuppressant. Binds to FKBP12 and inhibits calcineurin and NFAT. Displays anti-inflammatory effects in skin diseases. Cell permeable and active in vivo.
$67.00 – $228.00
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Product Details
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 792
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References
1. Hatanaka, H., et al., (1988) J. Antibiot. (Tokyo), 41 : 1592
2. Petros, A.M., et al., (1991) J. Med. Chem., 34 : 2925
3. Mollison, K.W., et al., (1999) J. Invest. Dermatol., 112 : 729
