Losartan Potassium

Non-peptide angiotensin II receptor antagonist. Clinically useful antihypertensive agent. Inhibits collagen I synthesis. Induces SIRT1 expression and activity and reduces hepatic injury in a rat reduced-size orthotopic liver transplantation model. Displays neuroprotective effects along with nimesulide against chronic fatigue stress. Displays myocardial antifibrotic activity.

Catalog ID: CV-1021

$76.00 – $304.00

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  • Product Details
    • Physical State: Off-white powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 461

  • References

    1. Merck 14 : 5583
    2. Chiu, A.T., et al., (1990) J. Pharmacol. Exp. Ther., 252 : 711
    3. McIntyre, M., et al., (1997) Pharmacol. Ther., 74 : 181
    4. Diop-Frimpong, B., et al., (2011) Proc. Natl. Acad. Sci. USA, 108 : 2909
    5. Pantazi, E., et al., (2015) World J. Gastroenterol., 21 : 8021
    6. Kumar, A., et al., (2015) Inflammopharmacology, 23 : 291
    7. Miguel-Carrasco, J.L., et al., (2017) Sci. Rep., 7 : 41865

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