PRE084

PRE-084 is an agonist of the σ receptor with selectivity for the σ1 subtype (IC50: σ1=2.2 nM, σ2=13091 nM). PRE-084 has demonstrated neuroprotective/restorative effects in brain injury, and neurodegenerative conditions.

Catalog ID: CV-1039

$95.00 – $333.00

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  • Product Details
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 353.9

  • References

    1. Su, T.P., et al., (1991) J. Pharmacol. Exp. Ther., 259 : 543
    2. Griesmaier, E., et al., (2012) Exp. Neurol., 237 : 388
    3. Dong, H., et al., (2016) Cell Mol. Neurobiol., 36 : 639
    4. Guzman-Lenis, M.S., et al., (2009) Neuroscience, 162 : 31
    5. Hyrskyluoto, A., et al., (2013) Cell Death Dis., 4 : e646
    6. Francardo, V., et al., (2014) Brain, 137(Pt 7) : 1998
    7. Mancuso, R., et al., (2012) Neurotherapeutics, 9 : 814

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