Diazoxide
Activates ATP-dependent K+ channels 1 via inducing translocation of PKC-epsilon from the cytosol to the mitochondria 2. Hyperglycemic agent. Induces powerful protective effects against cardiac ischemia via multiple mechanisms 3. Stimulates mitochondrial ATP synthase activity conferring cardioprotection in a streptozotocin-induced acute diabetes model 4. Prevents alterations in memory and synaptic plasticity induced by Amyloid-Beta 5.
$78.00 – $228.00
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Product Details
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 230.7
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References
1. Trube, G., et al., (1986) Pflugers Arch., 407 : 493
2. Kim, M.Y., et al., (2006) Br. J. Pharmacol., 149 : 1059
3. Coetzee, W.A., et al., (2013) Pharmacol. Ther., 140 : 167
4. Jasova, M., et al., (2016) Physiol. Res., 65 Suppl 1 : S119
5. Salgado-Puga, K., et al., (2017) J. Alzheimers Dis., 57 : 205
