Ascomycin

Analog of FK-506. Potent immunosuppressant. Binds to FKBP12 and inhibits calcineurin and NFAT. Displays anti-inflammatory effects in skin diseases. Cell permeable and active in vivo.

Catalog ID: CV-1014-2

$228.00

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  • Product Details
    • Size: 25.0mg
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 792

  • References

    1. Hatanaka, H., et al., (1988) J. Antibiot. (Tokyo), 41 : 1592
    2. Petros, A.M., et al., (1991) J. Med. Chem., 34 : 2925
    3. Mollison, K.W., et al., (1999) J. Invest. Dermatol., 112 : 729

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