BD1047 dihydrobromide

BD1047 is a potent and selective sigma-1 antagonist (IC50’s: σ1=0.93 nM, σ2=47 nM). It reduced convulsions, lethality, and locomotor activity induced by cocaine in mouse models. BD1047 attenuated high fat diet-induced peripheral neuropathy in mice. BD1047 displayed antinociceptive effects in several rodent pain models. It also inhibits the β-adrenergic receptor (IC50=145 nM).

Catalog ID: CV-1041-2

$371.00

  • Product Details

    • Size: 25.0 mg
    • Physical State: Off-white powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 437
  • References

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