Tau 4G11
Product background: The Tau proteins are a family of neuronal microtubule associated proteins that are found in the neurofibrillary tangles often associated with Alzheimer’s Disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells.
About the product: Tau-4G11 (TA-1001) is a rPeptide exclusive Tau mouse monoclonal antibody that binds 4 out of the 6 Tau isoforms. This antibody specifically binds Tau-381, Tau-410, Tau-412, and Tau-441 which all contain at least one amino terminal insert.
Applications: This anti-Tau mouse derived monoclonal antibody specifically recognizes four out of six Tau isoforms. Possible applications could include isoform identification, qualitative analysis, or expression level monitoring through western blots, ELISAs, or other methods.
$275.00
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Product Details
- Size: 100 µg
- Host: Mouse
- Reactivity Species: Human
- Physical State: Liquid
- Temperature Storage: -80°C
- Temperature Shipping: Dry Ice
- Purity: >90% by SDS-PAGE
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References
1. Avila, J., et al., (2004) Physiol Rev., 84 : 361
2. Goedert, M., (1993) Trends Neurosci., 16 : 460
3. Mandelkow, E., et al., (1996) Ann N Y Acad Sci., 777 : 96
4. Goedert, M., et al., (1989) Neuron., 3 : 519
5. Himmler, et al., (1989) Mol Cell Biol., 9 : 1381
6. Tai, C., et al., (2020) Neuron., 106(3) : 421-437.e11
7. Nobuhara, C., et al., (2017) Am J Pathol., 187(6) : 1399–1412
