Benztropine Mesylate
Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat) 1. Also inhibits the dopamine transporter (Ki=160 nM) 2. Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents 3. Inhibits hepatitis C virus infection 4.
$76.00
Out of stock
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Product Details
- Size: 1 gm
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 403.5
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References
1. Zhang, Y., et al., (2001) J. Med. Chem., 44 : 3937
2. Schmitt, K.C., et al., (2008) J. Neurochem., 107 : 928
3. Deshmukh, V.A., et al., (2013) Nature, 502 : 327
4. Mingorance, L., et al., (2014) Antimicrob. Agents Chemother, 58 : 3451
