Beta-Amyloid (1-40), Mouse, Rat

Product background: Beta-Amyloid peptides (A-beta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be a primary contributor to Alzheimer’s Disease (AD).

About the product: Expressed recombinantly in E. coli, the mouse/rat Beta-Amyloid (1-40) is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.

Applications: Beta-Amyloid (1-40), mouse/rat peptide is supplied in the NH4OH counter-ion ensuring a highly monomeric starting material that may be suited to aggregation studies, seeding experiments, molecular standards and more.

Catalog ID: A-1007-1

$225.00

  • Product Details

    • Size: 0.5 mg
    • Physical State: White lyophilized powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Sequence:
      D A E F G H D S G F E V R H Q K L V F F A E D V G S N K G A I I G L M V G G V V
    • Source: Recombinant. A DNA sequence encoding the mouse/rat beta-amyloid (1-40) sequence was expressed in E. coli
    • Purity: >97% by Mass Spec.
    • Molecular Mass: 4,329 Da theoretical
  • References

    1. Yankner, B., et al., (1990) Science, 250 : 279-282
    2. Stine, W., et al., (2003) J. Biol. Chem, 278 : 11612-11622
    3. Frank, R., et al., (2003) Neurobiology of Aging, 24 : 521-536
    4. Alsalahat, I., et al., (2021) Biochemistry and Biophysics Reports, 26 : 100943

  • Publications

    Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

    Cell Reports (2023) 42 (10), 113240 DOI: 10.1016/j.celrep.2023.113240

    Wu, Du, Bimler et al