Beta-Amyloid (1-42), Mouse, Rat
Product background: Beta-Amyloid peptides (A-beta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be a primary contributor to Alzheimer’s Disease (AD).
About the product: Expressed recombinantly in E. coli, the mouse/rat Beta-Amyloid (1-42) is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.
Applications: Beta-Amyloid (1-42), mouse/rat peptide is supplied in the NH4OH counter-ion ensuring a highly monomeric starting material that may be suited to aggregation studies, seeding experiments, molecular standards and more.
$285.00 – $495.00
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Product Details
- Physical State: White lyophilized powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Sequence:
D A E F G H D S G F E V R H Q K L V F F A E D V G S N K G A I I G L M V G G V V I A
- Source: Recombinant. A DNA sequence encoding the mouse/rat beta-amyloid (1-42) sequence was expressed in E. coli
- Purity: >97% by Mass Spec.
- Molecular Mass: 4,417Da theoretical
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References
1. Yankner, B., et al., (1990) Science, 250 : 279-282
2. Stine, W., et al., (2003) J. Biol. Chem, 278 : 11612-11622
3. Frank, R., et al., (2003) Neurobiology of Aging, 24 : 521-536
4. Gericke, C., et al., (2020) Front. Immunol., 11 : 1029 -
Publications
bioRxiv; https://doi.org/10.1101/598540.
Cell Reports (2023) 42 (10), 113240 DOI: 10.1016/j.celrep.2023.113240
