Camostat Mesylate

A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis. Reduces weight gain and improves metabol-ism in obese rodent models. In clinical use (in Japan) for pancreatitis. Inhibits influenza virus replication in human tracheal epithelial cells. Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.

Catalog ID: CV-1019

$76.00 – $238.00

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  • Product Details
    • Physical State: Off-white powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 494.5

  • References

    1. Gibo, J., et al., (2005) Lab. Invest., 85 : 75
    2. Albarazanji, K., et al., (2019) Am. J. Physiol. Gastrointest. Liver Physiol., 316 : G653
    3. Ueda, M., et al., (2015) Nephron, 129 : 223
    4. Yamaya, M., et al., (2015) Pulm. Pharmacol. Ther., 33 : 66
    5. Hoffmann, M., et al., (2020) Cell, 181 : 1

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