Captopril
Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 0.022 μM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4 formation and Ki = 60 nM for L-lysine-p-nitroanilide). Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.
$152.00
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Product Details
- Size: 5 g
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 217.3
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References
1. Cushman, D.W., et al., (1999) Nat. Med., 5 : 1110
2. Orning, L., et al., (1991) J. Biol. Chem., 266 : 16507
