FK-506

FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM) 1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson’s disease 2. Increases the rate of axonal regeneration following crush injury in a rat model 3. Cell permeable.

Catalog ID: N-3024

$190.00 – $665.00

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  • Product Details
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 804

  • References

    1. Yu, D.Y., et al., (2006) IUBMB Life, 58 : 429
    2. Van Der Perren, A., et al., (2015) Neurobiol. Aging, 36 : 155
    3. Sun, H.H., et al., (2012) Neuroscience, 223 : 114

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