Fluorescein-r Beta-Amyloid (1-42)
Product background: Beta-Amyloid peptides (A-beta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be a primary contributor to Alzheimer’s Disease (AD).
About the product: Expressed recombinantly in E. coli, Beta-Amyloid (1-42) is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality. rPeptide’s human Beta-Amyloid has been covalently labeled with Fluorescein Isothiocyanate on the side chain of lysine residues.
Applications: This FITC labeled form of Beta-Amyloid (1-42) is ideally suited to localization experiments, aggregation monitoring and other fluorescence based studies without the need for mutations or further labeling.
$650.00 – $900.00
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Product Details
- Physical State: Lyophilized powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Sequence:
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
- Source: Recombinant. A DNA sequence encoding the human beta-amyloid (1-42) sequence was expressed in E. coli and had FITC molecules attached for fluorescence
- Purity: >95% by Mass Spec.
- Molecular Mass: Approximately 4,514 Da to 5,293 Da
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References
1. Jin, S., et al., (2016) Journal of Biological Chemistry. 291 : 19590-19606
2. Jamasbi, E., et al., (2018) Biochimica et Biophysica Acta (BBA) 1860(9) : 1609-1615
3. Jungbauer, L.M., et al., (2009) J Mol Recognit. 22(5) : 403-413
