N4-Hydroxycytidine

N4-Hydroxycytidine was originally identified as a mutagen effecting AT to GC base-pair transitions. It has also been found to have antiviral properties against a broad range of viruses including hepatitis C, norovirus, Ebola virus, influenza and respiratory syncytial viruses and coronaviruses. Active molecule in the antiviral pro-drug clinical candidate EIDD-2801.

Catalog ID: CV-1029

$133.00$475.00

  • Product Details

    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 259.2
  • References

    1. Janion, C., and Glickman, B.W., (1980) Mutat. Res., 72 : 43
    2. Stuyver, L.J., et al., (2003) Antimicrob. Agents Chemother., 47 : 244
    3. Costantini, V.P., et al., (2012) Antivir. Ther., 1 : 981
    4. Reynard, O., et al., (2015) Viruses, 7 : 6233
    5. Yoon, J.J., et al., (2018) Antimicrob. Agents Chemother., 62 : e00766-18
    6. Pyrc, K., et al., (2006) Antimicrob. Agents Chemother., 50 : 2000
    7. Toots, M., et al., (2019) Sci. Transl. Med., 11 : eaax5866