N4-Hydroxycytidine
N4-Hydroxycytidine was originally identified as a mutagen effecting AT to GC base-pair transitions. It has also been found to have antiviral properties against a broad range of viruses including hepatitis C, norovirus, Ebola virus, influenza and respiratory syncytial viruses and coronaviruses. Active molecule in the antiviral pro-drug clinical candidate EIDD-2801.
$133.00 – $475.00
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Product Details
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 259.2
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References
1. Janion, C., and Glickman, B.W., (1980) Mutat. Res., 72 : 43
2. Stuyver, L.J., et al., (2003) Antimicrob. Agents Chemother., 47 : 244
3. Costantini, V.P., et al., (2012) Antivir. Ther., 1 : 981
4. Reynard, O., et al., (2015) Viruses, 7 : 6233
5. Yoon, J.J., et al., (2018) Antimicrob. Agents Chemother., 62 : e00766-18
6. Pyrc, K., et al., (2006) Antimicrob. Agents Chemother., 50 : 2000
7. Toots, M., et al., (2019) Sci. Transl. Med., 11 : eaax5866