Pinacidil
Activates ATP-dependent potassium channels 1,2. Induces vascular relaxation and antihypertensive effects 3. Prevents the loss of mitochondrial inner membrane potential, protecting cerebellar granule neurons from apoptosis induced by oxidative stress 4. Displays protective effects in Parkinson’s disease models 5 and cerebral ischemia-reperfusion 6.
$57.00 – $190.00
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Product Details
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 263.3
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References
1. Hermsmeyer, RK. et al., (1988) J. Cardiovasc. Pharmacol., 12 (Suppl 2):S17
2. Gollasch, M., et al., (1995) J. Pharmacol. Exp. Therap., 275 : 681
3. Cohen, M.L., et al., (1988) J. Cardiovasc. Pharmacol., 12 (Suppl 2):S5
4. Teshima, Y., et al., (2003) Stroke, 34 : 1796
5. Xie, J., et al., (2010) J. Neurosci. Res., 88 : 428
6. Zhang, H., et al., (2008) Neurosci. Bull., 24 : 7
