Plasminogen, Human
Product background: Plasminogen is the precursor of Plasmin, which is a protease present in blood that is involved in the degradation of Abeta peptides. The conversion of Plasminogen to Plasmin is mediated by 2 Plasminogen activators, to allow APP alpha-cleavage and Beta-Amyloid degradation. Both of these reactions are reduced in patients with Alzheimer’s Disease.
About the product: Human Plasminogen is purified from human plasma and is sold as a lyophilized powder in 20mM Tris-HCl pH 7.5 with 2mM EDTA.
Applications: Human Plasminogen is in a native form and may be suitable for cellular assays, aggregation studies or as a therapeutic target.
$97.00
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Product Details
- Size: 1.0 mg
- Physical State: Lyophilized from 20 mM Tris-HCl, pH 7.5, with 2 mM EDTA
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Purity: >95% by SDS-PAGE
- Molecular Mass: 90,000 to 92,000 Da
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References
1.Melchor, J.P., et al., (2003) The Journal of Neuroscience, 23(26) : 8867-8871
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Publications
Hindawi; https://doi.org/10.1155/2017/6093017.
