Pridopidine
Potential treatment for Huntington’s disease, Parkinson’s disease, and schizophrenia. Able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics (“dopamine stabilizer”). More recent studies have attributed pridopidine’s effects to its being a more potent sigma-1 ligand than a D2 ligand. Displays neuroprotective/restorative effects and ameliorates central features of amyotrophic lateral sclerosis pathology in a sigma-1-mediated manner.
$152.00
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Product Details
- Size: 5.0 mg
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 281.4
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References
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8. Lonescu, A., et al., (2019) Cell Death Dis., 10 : 210
