Rapamycin
Potent immunosuppressant. The rapamycin-FKBP12 complex binds to and inhibits mTOR.Inhibits IL-2-induced activation of p70 S6 kinase. Extends lifespan of mice. Induces autophagy in a variety of cell lines.
$95.00 – $342.00
-
Product Details
- Physical State: White powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
-
References
1. Huang, S., et al., (2003) Cancer Biol. Ther., 2 : 222
2. Kuo, C.J., et al., (1992) Nature, 358 : 70
3. Harrison, D.E., et al., (2009) Nature, 460 : 392
4. Flemming, A., et al., (2011) Nat. Chem. Biol., 7 : 9
