Rapamycin
Potent immunosuppressant. The rapamycin-FKBP12 complex binds to and inhibits mTOR 1. Inhibits IL-2-induced activation of p70 S6 kinase 2. Extends lifespan of mice 3. Induces autophagy in a variety of cell lines 4.
$190.00 – $665.00
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Product Details
- Physical State: White crystalline powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 914.2
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References
1. Huang, S., et al., (2003) Cancer Biol. Ther., 2 : 222
2. Kuo, C.J., et al., (1992) Nature, 358 : 70
3. Harrison, D.E., et al., (2009) Nature, 460 : 392
4. Flemming, A., et al., (2011) Nat. Chem. Biol., 7 : 9
