SA4503

SA4503 is a potent and selective sigma 1 agonist (σ1 IC50=17.4 nM, σ2 IC50=1784 nM). It has been investigated as a cognition enhancer, antidepressant, anti-addiction agent, and neuroprotectant.

Catalog ID: CV-1042

$124.00 – $418.00

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  • Product Details
    • Physical State: White powder
    • Temperature Storage: -20°C
    • Temperature Shipping: Ambient
    • Molecular Mass: 441.4

  • References

    1. Matsuno, K., et al., (1996) Eur. J. Pharmacol., 306 : 271
    2. Matsuno, K., et al., (1997) Behav. Brain Res., 83 : 221
    3. Niitsu, T., et al., (2012) Curr. Pharm. Des., 18 : 875
    4. Skuza, G., and Rogoz, Z., (2002) Behav. Pharmacol., 13 : 537
    5. Lucas, G., et al., (2008) Int. J. Neuropsychopharmacol., 11 : 485
    6. Mori, T., et al., (2014) Addict. Biol., 19 : 362
    7. Nakazawa, M., et al., (1998) Neurochem. Int., 32 : 337
    8. Ruscher, K., et al., (2011) Brain, 134(Pt3) : 732
    9. Ruscher, K., et al., (2012) PLoS One, 7 : e45118
    10.Yamashita, D., et al., (2015) Int. J. Neurosci. Res., 93 : 788

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