Salirasib
Displaces active Ras protein from the plasma membrane inhibiting its activity, IC50=10-15 µM 1. Enhances autophagy in a variety of cell lines 2. Protects against HIV-1-induced accumulation of Aβ in human brain microvascular endothelial cells 3. Displays antiinflammatory activity, inhibiting the release of PGD2 and TNFα from mast cells 4.
$57.00 – $228.00
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Product Details
- Physical State: White crystalline powder
- Temperature Storage: -20°C
- Temperature Shipping: Ambient
- Molecular Mass: 358.5
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References
1. Haklai, R., et al., (1998) Biochemistry, 37 : 1306
2. Schmuckler, E., et al., (2013) Oncotarget, 4 : 145
3. Andras, I.E., et al., (2012) Biochem. Biophys. Res. Commun., 421 : 177
4. Mor, A., et al., (2011) Inflammation, 34 : 314
