Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells
Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease (2023) 1869 (7), 166793 DOI: 10.1016/j.bbadis.2023.166793
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
Acta Neuropathologica Communications (2023) 11 (1), 135 DOI: 10.1186/s40478-023-01633-7
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease
Mol Cell Proteomics (2023) 22 (5), 100542 DOI: 10.1016/j.mcpro.2023.100542
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
Cell Reports (2023) 42 (7), 112725 DOI: 10.1016/j.celrep.2023.112725
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
Cell Reports (2023) 42 (10), 113240 DOI: 10.1016/j.celrep.2023.113240
Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline
Alzheimer’s Research and Therapy (2023) 15 (1), 2 DOI: 10.1186/s13195-022-01143-z
Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats
Alzheimer’s Research and Therapy (2023) 15 (1), 174 DOI: 10.1186/s13195-023-01316-4
Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate
Cell Death & Disease (2023) 14 (3), 192 DOI: 10.1038/s41419-023-05714-2
Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease
Autophagy (2023) 19 (8), 2318-2337 DOI: 10.1080/15548627.2023.2181614
A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers
Journal of the American Chemical Society (2023) 145 (33), 18340-18354 DOI: 10.1021/jacs.3c03980