Publications
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Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Springer Berlin Heidelberg; https://doi.org/10.1007/s00401-019-01993-2.
Di Hu, Xiaoyan Sun, Xudong Liao, Xinwen Zhang, Sara Zarabi,..Xin Qi (2018) -
Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity.
The Journal of Nutritional Biochemistry; https://doi.org/10.1016/j.jnutbio.2018.10.019.
Lap Ho, Danyue Zhao, Kenjiro Ono, Kai Ruan, Ilaria Mogno, Mayumi Tsuji, Eileen Carry, Justin Brathwaite, Steven Sims, Tal Frolinger, Susan Westfall, Paolo Mazzola, Qingli Wu, Ke Hao, Thomas E. Lloyd, James E. Simon, Jeremiah Faith, Giulio M. Pasinetti (2018) -
Measuring Mitochondrial Dysfunction Caused by Soluble α-Synuclein Oligomers.
Humana Press, New York, NY; https://doi.org/10.1007/978-1-4939-9124-2_14.
Eric S. Luth, Irina G. Stavrovskaya (2018) -
Seeding variability of different alpha synuclein strains in synucleinopathies.
Annals of Neurology; https://doi.org/10.1002/ana.25446.
Candelise, Schmitz, Llorens et al (2018) -
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson’s Disease Etiopathology.
Springer; https://doi.org/10.1007/s12035-018-1082-0.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk M. Jęśko, Wojciech Hilgier, Robert Brodzik, Magdalena Gąssowska-Dobrowolska, Carsten Culmsee, Agata Adamczyk (2018) -
Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses.
Journal of Neuroscience; https://doi.org/10.1101/517524.
Susan M.L. Banks, Audrey T. Medeiros, Molly McQuillan, David J. Busch, Ana Sofia Ibarraran-Viniegra, Subhojit Roy, Rui Sousa, Eileen M. Lafer, Jennifer R. Morgan (2018) -
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer’s Disease.
J Alzheimers Dis.; doi: 10.3233/JAD-190604.
Huseby, Carol J., Hoffman, Claire N., Cooper, Grace L., Cocuron, Jean-Christophe., Alonso, Ana P., Thomas, Stefani N., Yang, Austin J., Kuret, J. (2018) -
Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation.
J Biol Chem.; doi: 10.1074/jbc.RA119.009487.
Takashi Saito, Naomi Mihira, Yukio Matsuba, Hiroki Sasaguri, Shoko Hashimoto, Sneha Narasimhan,Bin Zhang, Shigeo Murayama,Makoto Higuchi, Virginia M.Y. Lee, John Q Trojanowski, Takaomi C. Saido (2018) -
Highly sensitive quantification of Alzheimer's disease biomarkers by aptamer-assisted amplification.
Theranostics; DOI: 10.7150/thno.29232.
Hei-Nga Chan, Di Xu, See-Lok Ho, Dinggeng He, Man Shing Wong, Hung-Wing Li (2018) -
Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard.
Journal of Proteome Research; https://doi.org/10.1021/acs.jproteome.8b00920.
Maotian Zhou, Duc M Duong, Erik C.B. Johnson, Jingting Dai, James J Lah, Allan I. Levey, and Nicholas T. Seyfried (2018) -
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Nature Communications; https://doi.org/10.1038/s41467-019-09291-x.
Yuanyuan Zhao, Xiaoyan Sun, Di Hu, Domenick A. Prosdocimo, Charles Hoppel, Mukesh K. Jain, Rajesh Ramachandran & Xin Qi (2018) -
Dural lymphatics regulate clearance of extracellular tau from the CNS.
BioMed Central; https://doi.org/10.1186/s13024-019-0312-x.
Tirth K. PatelLeMoyne Habimana-GriffinXuefeng GaoBaogang XuSamuel Achilefu,....David M. Holtzman (2018) -
Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.
Science Advances; DOI: 10.1126/sciadv.aau3333
Stephen S. Dominy, Casey lynch, Florian Ermini, Malgorzata Benedyk, Agata Marczyk,...Jan Potempa (2018) -
Amyloid-β/Drug Interactions from Computer Simulations and Cell-Based Assays
IOS Press; DOI 10.3233/JAD-179902.
Nguyen, Phuong H., del Castillo-Frias, Maria P., Berthoumieux, Olivia ,Faller, Peter, Doig, Andrew J., Derreumaux, Philippe (2018) -
Medical Plants and Nutraceuticals for Amyloid- Beta Fibrillation Inhibition
IOS Press; DOI 10.3233/ADR-180066.
Steffi Witter, Raiker Witter, Raivo Vilu and Ago Samoson (2018) -
Inflammation-induced Iron Transport and Metabolism by Brain Microglia.
JBC; DOI: 10.3233/JAD-170961.
McCarthy,R.C., Sosa,J.C., Gardeck, A.M., Baez,A.S., Lee,C., Wessling-Resnick,M. (2018) -
Light-triggered dissociation of self-assembled β-amyloid aggregates into small, nontoxic fragments by ruthenium (II) complex.
Acta Biomaterialia; https://doi.org/10.1016/j.actbio.2017.11.048.
Giyeong Son, Byung Il Lee, You Jung Chung, Chan Beum Park (2018) -
Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression
Acta Neuropathologica Communications; https://doi.org/10.1186/s40478-018-0529-x.
Alejandro Ruiz-Riquelme†, Heather H. C. Lau†, Erica Stuart, Adrienn N. Goczi, Zhilan Wang, Gerold Schmitt-Ulms and (2018) -
Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine.
Bioorganic & Medicinal Chemistry; DOI: 10.1016/j.bmc.2018.01.028.
Mizuho Hanaki, Kazuma Murakami, Sumie Katayama, Ken-ichi Akagi, Kazuhiro Irie (2018) -
Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease
Wiley Online Library; https://doi.org/10.15252/emmm.201708300
Steeland, Gorlé , Vandendriessche et al. (2018)
