Publications
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Identification of dibenzyl imidazolidine and triazole acetamide derivatives through virtual screening targeting amyloid beta aggregation and neurotoxicity in PC12 cells.
Science Direct European Journal of Medicinal Chemistry; http://dx.doi.org/10.1016/j.ejmech.2017.02.057.
Sukanya Das, Scott D. Smid (2017) -
Anti-amyloid aggregation activity of novel carotenoids: implications for Alzheimer’s drug discovery.
Clinical Interventions in Aging; doi: 10.2147/CIA.S134605
Lakey-Beitia, Johant et al. (2017) -
Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice.
Journal of Neuroscience Research; doi: 10.1002/jnr.23880.
Hao Cui, Anna E. King, Glenn A. Jacobson, David H. Small (2017) -
7-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-4E-hepten-3-one alleviates Aβ1-42 induced cytotoxicity through PI3K-mTOR pathways.
Biochemical and Biophysical Research Communications; doi: 10.1016/j.bbrc.2017.01.125.
Panel Hanlin Xiao, Qinghua Zhang, Yinghui Peng Genyun Tang, Yumei Liao, Xiaoji Zhuang, Wen-Cai Ye, Ying Wang, Lei Shi (2017) -
USE FOR CALIBRATION OF CERTIFIED REFERENCE MATERIALS FOR Aβ1-42.
Alzheimer’s and Dementia; DOI: 10.1016/j.jalz.2017.07.630.
Boulo,Kuhlmann, Bittner et al (2017) -
Structure dependent effects of Amyloid-β on long-term memory in Lymnaea stagnalis.
The Febs Journal; 10.1002/1873-3468.12633.
Lenzie Ford, Michael Crossley, Devkee M Vadukul, Gyorgy Kemenes, Louise C Serpell (2017) -
Development of multifunctional heterocyclic Schiff base as a potential metal chelator: a comprehensive spectroscopic approach towards drug discovery.
J Biol Inorg Chem.; doi: 10.1007/s00775-016-1407-2.
Manojkumar Jadhao, Chayan Das, Anoop Rawat, Himank Kumar, Ritika Joshi, Sudipta Maiti, Sujit Kumar Ghosh (2017) -
NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer’s Disease.
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-151203.
Manocha, Gunjan D, Ghatak, Atreyi, Puig, Kendra L, Kraner, Susan D, Norris, Christopher M, Combs, Colin K (2017) -
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
Biochim Biophys Acta Mol Basis Dis.; doi: 10.1016/j.bbadis.2016.11.020.
Gazova, Soukup, Sepsova, et al (2017) -
Multivalent foldamer-based affinity assay for selective recognition of Aβ oligomers.
Analytica Chimica Acta; https://doi.org/10.1016/j.aca.2017.01.013.
Gábor Olajos, Éva Bartus, Ildikó Schuster, Gergely Lautner, Róbert E.Gyurcsányi, Titanilla Szögi, Lívia Fülöp, Tamás A.Martinek (2017) -
Amyloid-beta Peptide Decreases Expression and Function of Glutamate Transporters in Nervous System Cells.
The International Journal of Biochemistry & Cell Biology; http://dx.doi.org/10.1016/j.biocel.2017.01.017.
Tonga, Zhang, Menga, et al (2017) -
Elucidating the Aβ42 Anti-Aggregation Mechanism of Action of Tramiprosate in Alzheimer’s Disease: Integrating Molecular Analytical Methods, Pharmacokinetic and Clinical Data.
CNS Drugs; 10.1007/s40263-017-0434-z.
Kocis, P., Tolar, M., Yu, J. et al. (2017) -
Rattle-Structured Upconversion Nanoparticles for Near-IR-Induced Suppression of Alzheimer's β-Amyloid Aggregation
Small; DOI:10.1002/smll.201603139.
Kuk, Lee, Lee, et al (2017) -
Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease.
PLOS One; doi: 10.1371/journal.pone.0182194.
Drolle, Negoda,Hammond, et al (2017) -
Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42.
FEBS Letters; https://doi.org/10.1002/1873-3468.12590.
Vadukul , Gbajumo , Marshall , et al (2017) -
Covalent modifications of the amyloid beta peptide by hydroxynonenal: Effects on metal ion binding by monomers and insights into the fibril topology.
Journal of Inorganic Biochemistry; DOI: 10.1016/j.jinorgbio.2017.06.007.
G.Grasso, P.H.Axelsen, H.Komatsu (2017) -
Carbon Nanodot‐Sensitized Modulation of Alzheimer's β‐Amyloid Self‐Assembly, Disassembly, and Toxicity.
Small; doi: 10.1002/smll.201700983.
You Jung Chung, Kayoung Kim, Byung Il Lee, Chan Beum Park (2017) -
PROGRESS ON THE DEVELOPMENT OF CERTIFIED REFERENCE MATERIALS FOR Aβ1-42.
Journal of the Alzheimer’s Association; https://doi.org/10.1016/j.jalz.2017.07.629.
Boulo, Kuhlmann, Leinenbach et al (2017) -
Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways.
Science Direct Neurochemistry International; http://dx.doi.org/10.1016/j.neuint.2017.01.008.
F. Nafar, J.P. Clarke , K.M. Mearow (2017) -
Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer’s Disease.
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-170071.
Lakey-Beitia Johana, González Yisettb, Doens, Deborah, Stephens David E., Santamaría Ricardo, Murillo Enriquee, Gutiérrez Marcelino, Fernández Patricia L, Rao, K.S., Larionov Oleg V., Durant-Archibold Armando A, (2017)
