Publications
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Microglial Activation Results in Inhibition of TGF-β-Regulated Gene Expression.
J Mol Neurosci.; doi: 10.1007/s12031-017-0980-3.
Kwame Ofori Affram, Kendall Mitchell, Aviva J. Symes (2017) -
Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways.
Scientific Reports; https://doi.org/10.1038/s41598-017-08070-2.
Li Wang, Yilixiati Xiaokaiti, Gang Wang, Xiaoxiao Xu, Ling Chen, Xianfeng Huang, Li Liu, Jianchun Pan, Shuqun Hu, Zhuoyou Chen, Ying Xu (2017) -
Folding and Misfolding of Amyloid-β40 and 42 in Alzheimer’s Disease.
Biophysics and Biochemistry of Protein Aggregation; https://doi.org/10.1142/9789813202382_0007.
Yu-Jen Chang, Yun-Ru Chen (2017) -
Retro-inverso peptide inhibitor nanoparticles as potent inhibitors of aggregation of the Alzheimer's Aβ peptide.
Nanomedicine: Nanotechnology, Biology and Medicine; https://doi.org/10.1016/j.nano.2016.10.006.
Maria Gregori, Mark Taylor, Elisa Salvati, Simona Mancini, Claudia Balducci, Gianluigi Forloni, Vanessa Zambelli , Massimo Masserini, David Allsop (2017) -
P2X receptor overexpression induced by soluble oligomers of amyloid beta peptide potentiates synaptic failure and neuronal dyshomeostasis in cellular models of Alzheimer's disease.
Europe PMC; doi: 10.1016/j.neuropharm.2017.10.027.
Sáez-Orellana, Francisco, Fuentes-Fuentes, María C, Godoy, Pamela A, Silva-Grecchi, Tiare, Panes, Jessica D,…..Aguayo, Luis G. (2017) -
Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2′,3′,4′-trihydroxyflavone (2-D08).
Science Direct Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.05.041.
Dylan T. Marsha, Sukanya Dasa, Jessica Ridellb, Scott D. Smida, (2017) -
Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features
Movement Disorders; https://doi.org/10.1002/mds.27232.
Goldman, J.G., Andrews, H., Amara, A., et al (2016) -
The Ketone Body β-Hydroxybutyrate Does Not Inhibit Synuclein Mediated Inflammasome Activation in Microglia
Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-017-9754-5..
Vandana Deora, Eduardo A. Albornoz, Kevin Zhu, Trent M. Woodruff, Richard Gordon (2016) -
Comparison of Internal Standard Approaches for SRM Analysis of Alpha-Synuclein in Cerebrospinal Fluid
Journal of Proteome Research; 10.1021/acs.jproteome.7b00660.
Patrick Oeckl, Petra Steinacker, and Markus Otto (2016) -
Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.
Bioorganic & Medicinal Chemistry; https://doi.org/10.1016/j.bmc.2017.10.010.
Watanabe, Ariyoshi, Ozaki, et al (2016) -
Transmission of α-synuclein-containing erythrocyte-derived extracellular vesicles across the blood-brain barrier via adsorptive mediated transcytosis: another mechanism for initiation and progression of Parkinson’s disease?.
Acta Neuropathologica Communications; 10.1186/s40478-017-0470-4.
Matsumoto, J., Stewart, T., Sheng, L. et al. (2016) -
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles..
PLoS One; https://doi.org/10.1371/journal.pone.0181844.
Marika Doucet, Aadil El-Turabi, Franziska Zabel, Benjamin H.M. Hunn, Nora Bengoa-Vergniory, ilena Cioroch, Mauricio Ramm, Amy M. Smith, Ariane Cruz Gomes, Gustavo Cabral de Miranda, Richard Wade-Martins, Martin F. Bachmann (2016) -
Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-170342
Vasquez, Velmarini et al. (2016) -
Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies.
Journal of Neurochemistry; https://doi.org/10.1111/jnc.13974.
Miners; Love (2016) -
Levodopa (L-DOPA) attenuates endoplasmic reticulum stress response and cell death signaling through DRD2 in SH-SY5Y neuronal cells under α-synuclein-induced toxicity..
Neuroscience; doi: 10.1016/j.neuroscience.2017.06.060..
Juhyun Song, Byeong C.Kim, Dai-Trang T.Nguyen, Manikandan Samidurai, Seong-Min Choib (2016) -
MultiTEP platform–based DNA vaccines for alpha-synucleinopathies: pre clinical evaluation of immunogenicity and therapeutic potency.
Journal of the Alzheimer’s Association; https://doi.org/10.1016/j.neurobiolaging.2017.08.006
Davtyan, Hayk et al. (2016) -
Autoimmune antibody decline in Parkinson’s disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.
Molecular Neurodegeneration; https://doi.org/10.1186/s13024-017-0187-7.
Brudek, T., Winge, K., Folke, J. et al. (2016) -
Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)
Alzheimer’s Research & Therapy; https://doi.org/10.1186/s13195-017-0265-7.
Vanderstichele, H., Demeyer, L., Janelidze, S. et al. (2016) -
P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells.
Purinergic Signalling; DOI: 10.1007/s11302-017-9567-2.
Wilkaniec, A., Gąssowska, M., Czapski, G.A. et al. (2016) -
An extract of the marine alga Alaria esculenta modulates -synuclein folding and amyloid formation
Elsevier; http://dx.doi.org/10.1016/j.neulet.2017.02.055.
Giffin, Richards, Craft et al (2016)