Publications
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Amyloid-b peptides act as allosteric modulators of cholinergic signalling through formation of soluble BA b ACs.
Brain; doi: 10.1093/brain/awv318..
Rajnish Kumar, A. Nordberg, Taher Darreh-Shori (2016) -
Quantitative analysis of amyloid polymorphism using height histograms to correct for tip convolution effects in atomic force microscopy imaging.
RSC Advances; DOI:10.1039/C6RA24031C.
Yi-Chih Lina, Hiroaki Komatsub, Jianqiang Mac, Paul H. Axelsenb, Zahra Fakhraai (2016) -
Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta
BioMed Central; DOI: 10.1186/s12974-016-0484-z.
Ryan C. McCarthy, Dah-Yuu Lu, Ahmed Alkhateeb, Andrew M. Gardeck, Chih-Hao Lee, and Marianne Wessling-Resnick (2016) -
Structural insights into mechanisms for inhibiting amyloid β42 aggregation by non-catechol-type flavonoids. https://doi.org/10.1016/j.bmc.2015.12.021
Bioorg Med Chem; doi: 10.1016/j.bmc.2015.12.021.
Mizuho Hanaki, Kazuma Murakami, Ken-ichi Akagi, Kazuhiro Irie (2016) -
The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2)
Science Direct; http://dx.doi.org/10.1016/j.exer.2016.10.013.
George Taylor-Walkera, Savannah A. Lynna, Eloise Keelinga, Rosie Mundaya, David A. Johnstonb, Anton Pageb, Jennifer A. Scotta, Srini Goverdhana, Andrew J. Loterya, c, J. Arjuna Ratnayakaa, (2016) -
A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation.
Biomaterials; doi: 10.1016/j.biomaterials.2016.03.047.
Yinhui Li, Di Xu, See-Lok Ho, Hung-Wing Li, Ronghua Yang, Man Shing Wong (2016) -
Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer’s disease.
Acta Neuropathologica; doi: 10.1007/s00401-016-1558-9.
Katherine R. Sadleir, Patty C. Kandalepas, Virginie Buggia-Prévot, Daniel A. Nicholson, opal Thinakaran, Robert Vassar (2016) -
The Luminescent Oligothiophene p-FTAA Converts Toxic Aβ1–42 Species into Nontoxic Amyloid Fibers with Altered Properties.
Journal of Biological Chemistry; doi: 10.1074/jbc.M115.696229..
Livia Civitelli, Linnea Sandin, Erin Nelson, Sikander Iqbal Khattak, Ann-Christin Brorsson, Katarina Kågedal (2016) -
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DEGENERATIVE BRAIN DISEASE COMPRISING MULTI-TARGETING COMPOUNDS
freepatentsonline; .
Lim, Mi Hee (Ulsan, KR) (2016) -
Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells
Springer Link; DOI: 10.1007/s12264-016-0034-9.
Dema Najem, Michelle Bamji-Mirza, Ze Yang, Wandong Zhang (2016) -
Ketones block amyloid entry and improve cognition in an Alzheimer's model.
Neurobiol Aging.; doi: 10.1016/j.neurobiolaging.2015.11.018..
Jun Xiang Yin, Marwan Maalouf, Pengcheng Han, Minglei Zhao, Ming Gao, Turner Dharshaun, Christopher Ryan, Julian Whitelegge, Jie Wu, David Eisenberg, Eric M.Reiman, Felix E.Schweizer, Jiong Shi (2016) -
ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain.
Journal of Alzheimer’s Disease; doi: 10.3233/JAD-160456..
Fu Yu Hong, Hsiao Jen-Hsiang T., Paxinos George, Halliday Glenda M., Kim Woojin Scott (2016) -
The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease
Nature.com Scientific Reports; 10.1038/srep39171.
Youssra K. Al-Hilaly, Luca Biasetti, Ben J. F. Blakeman, Saskia J. Pollack, Shahin Zibaee, Alaa Abdul-Sada, Julian R. Thorpe, Wei-Feng Xue & Louise C. Serpell (2016) -
Regulatory factor X1 depresses ApoE-dependent Aβ uptake by miRNA-124 in microglial response to oxidative stress
Science Direct Neuroscience; dx.doi.org/10.1016/j.neuroscience.2016.12.017.
Chen-Zhuo Feng, Jin-Bo Yin, Jian-Jun Yang, Lin Cao (2016) -
Multifunctional quinoline-triazole derivatives as potential modulators of amyloid-β peptide aggregation
Journal of Inorganic Biochemistry; https://doi.org/10.1016/j.jinorgbio.2016.04.022.
Michael R.Jones, Christine Dyrager, Marie Hoarau, Kyle J. Korshavn, Mi Hee Lim, Ayyalusamy Ramamoorthy, Tim Storr (2016) -
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein.
Springer Link Cellular and Molecular Neurobiology; doi:10.1007/s10571-016-0454-0.
Leire Almandoz-Gil, Veronica Lindström, Jessica Sigvardson,Philipp J. Kahle, Lars Lannfelt, Martin Ingelsson, Joakim Bergström (2015) -
The involvement of dityrosine crosslinking in synuclein assembly and deposition in Lewy Bodies in Parkinson's disease..
Scientific Reports; http://doi.org/10.1038/srep39171.
Al-Hilaly, Youssra K and Biasetti, Luca and Blakeman, Ben J F and Pollack, Saskia J and Zibaee, Shahin and Abdul-Sada, Alaa and Thorpe, Julian R and Xue, Wei-Feng and Serpell, Louise C (2015) -
α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function..
EXP Neurol.; doi: 10.1016/j.expneurol.2016.09.003..
Wei-Li Kuan, Neal Bennett, Xiaoling He, Jeremy N. Skepper, Nataly Martynyuk, Ruwani Wijeyekoon, Prabhas V. Moghe, Roger A. Barker (2015) -
Anti-Inflammatory and Neuroprotective Effects of PGE2 EP4 Signaling in Models of Parkinson’s Disease..
Journal of Neuroimmune Pharmocology; doi: 10.1007/s11481-016-9713-6..
Suraj S. Pradhan, Kirstie Salinas, Alexis C. Garduno, Jenny U. Johansson, Qian Wang, Amy Manning-Bog (2015) -
5-HT2A Receptor Binding in the Frontal Cortex of Parkinson’s Disease Patients and Alpha-Synuclein Overexpressing Mice: A Postmortem Study.
Parkinson’s Disease; http://dx.doi.org/10.1155/2016/3682936.
Nadja Bredo Rasmussen, Mikkel Vestergaard Olesen, Tomasz Brudek, Per Plenge, Anders Bue Klein, Jenny E. Westin, Karina Fog, Gitta Wörtwein, Susana Aznar (2015)