Publications
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Anti-tau antibody reduces insoluble tau and decreases brain atrophy.
Wiley Online Library; DOI: 10.1002/acn3.176.
Kiran Yanamandra, Hong Jiang, Thomas E. Mahan, Susan E. Maloney, David F. Wozniak, Marc I. Diamond and David M. Holtzman (2014) -
Effects of Tau Domain-Specific Antibodies and Intravenous Immunoglobulin on Tau Aggregation and Aggregate Degradation.
ACS Publications; DOI: 10.1021/bi501272x.
Jose O. Esteves-Villanueva, Hanna Trzeciakiewicz, David A. Loeffler, and Sanela Martić (2014) -
On-chip detection of wild 3R, 4R and mutant 4R tau through kinesin-microtubule binding.
IEEE Xplore; doi: 10.1109/MEMSYS.2015.7050988.
Subramaniyan, S.P.; Tarhan, M.C.; Karsten, S.L.; Fujita, H.; Shintaku, H.; Kotera, H.; Yokokawa, R. (2014) -
Activity of Pramlintide, Rat and Human Amylin but not ABeta 1–42 at Human Amylin Receptors
pfizerpro.com; doi: 10.1210/en.2013-1658.
Joseph J. Gingell, Erica R. Burns, and Debbie L. Hay (2014) -
Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism
The Journal of Physical Chemistry; DOI: 10.1021/jp412743s.
Jason O. Matos, Greg Goldblatt, Jaekyun Jeon, Bo Chen, and Suren A. Tatulian (2014) -
Reduced Vascular Endothelial Growth Factor and Capillary Density in the Occipital Cortex in Dementia with Lewy Bodies
Brain Pathology; DOI: 10.1111/bpa.12130.
Scott Miners, Hayley Moulding, Rohan de Silva, andSeth Love (2014) -
Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands
Science Direct; DOI: 10.1016/j.bmc.2014.02.054.
Rob J.A. Nabuursa, Varsha V. Kapoerchanb, Athanasios Metaxasc, Sanne de Jongha, Maaike de Backera, Mick M. Wellinga, Wim Jiskootd, Albert D. Windhorstc, Hermen S. Overkleeftb, Mark A. van Buchema, Mark Overhandb, Louise van der Weerda (2014) -
Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides
ACS Publications; DOI: 10.1021/cn400183w.
Jacques Fantini, Coralie Di Scala, Nouara Yahi, Jean-Denis Troadec, Kevin Sadelli, Henri Chahinian, and Nicolas Garmy (2014) -
Regenerating the Brain: Stem Cell Differentiation and Cholinergic Dysfunction in Alzheimer Disease
Karolinska Institutet; .
Linn Malmsten (2014) -
Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B
Biopolymers; DOI: 10.1002/bip.22470.
Saketh Chemuru, Ravindra Kodali and Ronald Wetzel (2014) -
A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain
Wiley Online Library; DOI: 10.1111/jnc.12815.
Sergey V. Matveev, Hans Peter Spielmann, Brittney M. Metts, Jing Chen, Fredrick Onono, Haining Zhu, Stephen W. Scheff, Lary C. Walker, and Harry LeVine (2014) -
A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ
Science Direct; DOI: 10.1016/j.carbpol.2014.03.060.
Peipei Wang, Wenfeng Liao, Jianping Fang, Qin Liu, Jian Yao, Minghua Hu, Kan Ding (2014) -
Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry
Clinical Chemistry; DOI: 10.1373/clinchem.2013.216515.
Thomas McAvoy, Michael E. Lassman, Daniel S. Spellman, Zhenlian Ke, Bonnie J. Howell, Oitak Wong, Lan Zhu, Michael Tanen, Arie Struyk, Omar F. Laterza (2014) -
Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease
Wiley Online Library; DOI: 10.1111/acel.12281.
Silvia Maioli, Maria Lodeiro, Paula Merino-Serrais, Farshad Falahati, Wasim Khan, Elena Puerta, Alina Codita, Roberto Rimondini, Maria J. Ramirez, Andrew Simmons, Francisco Gil-Bea, Eric Westman, Angel Cedazo-Minguez1, and for the Alzheimer's Disease Neuroimaging Initiative (2014) -
Identification and Preclinical Pharmacology of the -Secretase Modulator BMS-869780
Hindawi; http://dx.doi.org/10.1155/2014/431858.
Jeremy H. Toyn,1 Lorin A. Thompson,2 Kimberley A. Lentz,3 Jere E. Meredith Jr.,1 Catherine R. Burton,1 Sethu Sankaranararyanan,1 Valerie Guss,1 Tracey Hall,1,4 Lawrence G. Iben,1 Carol M. Krause,1 Rudy Krause,1 Xu-Alan Lin,1 Maria Pierdomenico,1 Craig Polson,1 Alan S. Robertson,1 R. Rex Denton,3 James E. Grace,3 John Morrison,3 Joseph Raybon,3 Xiaoliang Zhuo,3 Kimberly Snow,3 Ramesh Padmanabha,5 Michele Agler,5,6 Kim Esposito,5 David Harden,5 Margaret Prack,5 Sam Varma,5,7 Victoria Wong,5,8 Yingjie Zhu,5,9 Tatyana Zvyaga,5 Samuel Gerritz,2 Lawrence R. Marcin,2 Mendi A. Higgins,2 Jianliang Shi,2 Cong Wei,10,11 Joseph L. Cantone,10 Dieter M. Drexler,10 John E. Macor,2 Richard E. Olson,2 Michael K. Ahlijanian,1 and Charles F. Albright1 (2014) -
A Synchrotron-based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Pre-fibrillar Intermediates with Residue-specific Resolution
ACS Publications; DOI: 10.1021/bi5010409.
Alexandra L Klinger, Janna Kiselar, Serguei Alekseyevich Ilchenko, Hiroaki Komatsu, Mark R. Chance, and Paul H Axelsen (2014) -
Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
Scientific Reports; doi:10.1038/srep04004.
Claire Tinker-Mill, Jennifer Mayes, David Allsop, & Oleg V. Kolosov (2014) -
Interaction studies of luminescent conjugated oligothiophenes with aggregated Amyloid β
Diva-Portal; doi:10.1385/1-59259-890-0:571.
Alexander Sandberg (2014) -
In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
Science Direct; doi:10.1016/j.brainres.2014.10.047.
Pietra Candela, Julien Saint-Pola, Marie-Christine Boucau, Fabien Gosselet, Laurence Fenart (2014) -
β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species
The Journal of Biological Chemistry; 10.1074/jbc.M113.525212.
Jennifer Mayes, Claire Tinker-Mill, Oleg Kolosov, Hao Zhang, Brian J. Tabner, and Daivd Allsop (2014)