Publications
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Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis.
PLOS ONE; DOI: 10.1371/journal.pone.0132604.
Gunjan D. Manocha, Kendra L. Puig, Susan A. Austin, Kathleen Seyb, Marcie A. Glicksman, Colin K. Combs (2015) -
A novel nicotinic mechanism underlies β-amyloid-induced neurotoxicity.
ScienceDirect; doi:10.1016/j.neuropharm.2015.04.025.
Qiang Liua, Xitao Xie, Sharareh Emadi, Michael R. Sierks, Jie Wu (2014) -
Identification of a specific α-synuclein peptide (α-Syn 29-40) capable of eliciting microglial superoxide production to damage dopaminergic neurons.
BioMed Central; DOI: 10.1186/s12974-016-0606-7.
Shijun Wang, Chun-Hsien Chu, Mingri Guo, Lulu Jiang, Hui Nie, Wei Zhang, Belinda Wilson, Li Yang, Tessandra Stewart, Jau-Shyong HongEmail author and Jing Zhang (2014) -
Altered Alpha-Synuclein, Parkin, and Synphilin Isoform Levels in Multiple System Atrophy Brains.
Wiley Online Library; DOI: 10.1111/jnc.13392.
Tomasz Brudek, Kristian Winge, Nadja Bredo Rasmussen, Justyna Maria Bahl Czarna, Julia Tanassi, Tina Klitmøller Agander, Thomas M. Hyde, and Bente Pakkenberg (2014) -
Insulin-degrading enzyme is activated by the C-terminus of α-synuclein.
Science Direct; doi:10.1016/j.bbrc.2015.09.002.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2014) -
Drugs which bind to alpha-synuclein. Neuroprotective or neurotoxic?.
ACS Chemical; DOI: 10.1021/acschemneuro.5b00172.
Joe Kakish, Dongsoo Lee, and Jeremy Stuart Lee (2014) -
Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of Parkinson's disease.
Oxford Journals; doi: 10.1093/hmg/ddv372.
Mari Suzuki, Nobuhiro Fujikake, Toshihide Takeuchi, Ayako Kohyama-Koganeya, Kazuki Nakajima, Yoshio Hirabayashi, Keiji Wada and Yoshitaka Nagai (2014) -
Insulin-degrading enzyme is activated by the C-terminus of α-synuclein.
ScienceDirect; doi:10.1016/j.bbrc.2015.09.002.
Sandeep K. Sharma, Erik Chorell, Pernilla Wittung-Stafshede (2014) -
Alpha-synuclein immunoreactivity patterns in the enteric nervous system.
ScienceDirect; doi:10.1016/j.neulet.2015.07.005.
Iban Aldecoa, Judith Navarro-Otano, Nadia Stefanova, Fabienne S. Sprenger, Klaus Seppi, Werner Poewe, Miriam Cuatrecasas, Francesc Valldeoriolab, c, Ellen Gelpif, Eduard Tolosa (2014) -
P2X7 receptor is critical in α-synuclein–mediated microglial NADPH oxidase activation..
Neurobiol. Aging; doi: 10.1016/j.neurobiolaging.2015.03.015.
Tianfang Jiang, Jake Hoekstra, Xin Heng, Wenyan Kang, Jianqing Ding, Jun Liu, Shengdi Chen, Jing Zhang (2014) -
Stabilization of Alpha-Synuclein Oligomers In Vitro by the Neurotransmitters, Dopamine and Norepinephrine: The Effect of Oxidized Catecholamines.
Springer Link; DOI: 10.1007/s11064-015-1597-y.
Andrew F. Fischer, Kathryn Mansfield Matera (2014) -
Alpha Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.
JBC Papers in Press; doi:10.1074/jbc.M115.641746.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee, and Sergey M. Bezrukov (2014) -
Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.
ScienceDirect; doi:10.1016/j.scr.2015.05.014.
Staffan Holmqvista, Marinka Brouwer, Mehdi Djelloul, Alejandro Garcia Diaz, Michael J. Devine, Anna Hammarbergf, Karina Fog, Tilo Kunath, Laurent Roybon (2014) -
Phenolic compounds prevent the oligomerization of α-synuclein and reduce synaptic toxicity.
JNC Journal of Neurochemistry; DOI: 10.1111/jnc.13180.
Ryoichi Takahashi, Kenjiro Ono, Yusaku Takamura, Mineyuki Mizuguchi, Tokuhei Ikeda, Hisao Nishijo andMasahito Yamada (2014) -
α-Synuclein Shows High Affinity Interaction with Voltage-dependent Anion Channel, Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M115.641746.
Tatiana K. Rostovtseva, Philip A. Gurnev, Olga Protchenko, David P. Hoogerheide, Thai Leong Yap, Caroline C. Philpott, Jennifer C. Lee and Sergey M. Bezrukov (2014) -
Tau protein, a biomarker of Alzheimer´s disease: in vitro phosphorylation and tau-reactive antibodies characterization.
Charles University; DOI 10.1002/jssc.201501045.
Lenka Hromádková (2014) -
Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
Nature; doi:10.1038/nn.4132.
Hirohide Asai, Seiko Ikezu, Satoshi Tsunoda, Maria Medalla, Jennifer Luebke, Tarik Haydar, Benjamin Wolozin, Oleg Butovsky, Sebastian Kügler & Tsuneya Ikezu (2014) -
Identification and characterization of natural antibodies against tau protein in an intravenous immunoglobulin product.
Science Direct; doi:10.1016/j.jneuroim.2015.10.017.
Lenka Hromadkova, Michala Kolarova, Barbora Jankovicova, Ales Bartos, Jan Ricny, Zuzana Bilkova, Daniela Ripova (2014) -
HUMAN ANTI-TAU ANTIBODIES.
Free Patents Online; http://www.freepatentsonline.com/y2015/0252102.html.
Nitsch, Roger; Chen, Feng; Grimm, Jan; Baeriswyl, Jean-luc; Hock, Christoph (2014) -
QUANTIFICATION OF TAU IN BIOLOGICAL SAMPLES BY IMMUNOAFFINITY ENRICHMENT AND MASS SPECTROMETRY.
Free Patents Online; http://www.freepatentsonline.com/y2015/0253341.html.
Mcavoy, Thomas, Lassman, Michael E., Laterza, Omar F. (2014)
