Publications
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A novel tau mutation, p.K317N, causes globular glial tauopathy.
Springer Link; doi:10.1007/s00401-015-1425-0.
Pawel Tacik , Michael DeTure , Wen-Lang Lin, Monica Sanchez Contreras, Aleksandra Wojtas, Kelly M. Hinkle, Shinsuke Fujioka, Matthew C. Baker, Ronald L. Walton , Yari Carlomagno, Patricia H. Brown, Audrey J. Strongosky, Naomi Kouri, Melissa E. Murray, Leonard Petrucelli, Keith A. Josephs, Rosa Rademakers, Owen A. Ross, Zbigniew K. Wszolek, Dennis W. Dickson (2014) -
Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta.
ScienceDirect; doi:10.1016/j.neurobiolaging.2015.08.022.
B. Michalski, M.M. Corrada, C.H. Kawas, M. Fahnestock (2014) -
Effects of antibodies to phosphorylated and non-phosphorylated tau on in vitro tau phosphorylation at Serine-199: Preliminary report.
ScienceDirect; doi:10.1016/j.exger.2015.04.010.
David A. Loeffler, Lynnae M. Smith, Andrea C. Klaver, Sanela Martić (2014) -
C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease.
The Journal of the Alzheimer’s Association; doi.org/10.1016/j.jalz.2015.05.012.
Ann De Vos , Dirk Jacobs , Hanne Struyfs , Erik Fransen , Kerstin Andersson , Erik Portelius , Ulf Andreasson , Didier De Surgeloose , Daniëlle Hernalsteen , Kristel Sleegers , Caroline Robberecht , Christine Van Broeckhoven , Henrik Zetterberg , Kaj Blennow , Sebastiaan Engelborghs , Eugeen Vanmechelen (2014) -
Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models.
PLOS One; DOI: 10.1371/journal.pone.0125614.
Sethu Sankaranarayanan, Donna M. Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory Cadelina, Nina Hoque, Lynn DeCarr, Stefanie Keenan, Alan Lin, Yang Cao, Bradley Snyder, Bin Zhang, Magdalena Nitla, Gregg Hirschfeld, Nestor Barrezueta, Craig Polson, Paul Wes, Vangipuram S. Rangan, Angela Cacace, Charles F. Albright, Jere Meredith Jr., John Q. Trojanowski, Virginia M-Y. Lee,Kurt R. Brunden, Michael Ahlijanian (2014) -
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
ScienceDirect; doi:10.1016/j.neurobiolaging.2014.12.004.
Miranda E. Orr, Valentina R. Garbarino, Angelica Salinas, Rochelle Buffenstein (2014) -
Human secreted tau increases amyloid-beta production.
ScienceDirect; doi:10.1016/j.neurobiolaging.2014.09.007.
Jessica Bright, Sami Hussain, Vu Dang, Sarah Wright, Bonnie Cooper, Tony Byun, Carla Ramos, Andrew Singh, Graham Parry, Nancy Stagliano, Irene Griswold-Prenner (2014) -
Anti-tau antibody reduces insoluble tau and decreases brain atrophy.
Wiley Online Library; DOI: 10.1002/acn3.176.
Kiran Yanamandra, Hong Jiang, Thomas E. Mahan, Susan E. Maloney, David F. Wozniak, Marc I. Diamond and David M. Holtzman (2014) -
Effects of Tau Domain-Specific Antibodies and Intravenous Immunoglobulin on Tau Aggregation and Aggregate Degradation.
ACS Publications; DOI: 10.1021/bi501272x.
Jose O. Esteves-Villanueva, Hanna Trzeciakiewicz, David A. Loeffler, and Sanela Martić (2014) -
On-chip detection of wild 3R, 4R and mutant 4R tau through kinesin-microtubule binding.
IEEE Xplore; doi: 10.1109/MEMSYS.2015.7050988.
Subramaniyan, S.P.; Tarhan, M.C.; Karsten, S.L.; Fujita, H.; Shintaku, H.; Kotera, H.; Yokokawa, R. (2014) -
Activity of Pramlintide, Rat and Human Amylin but not ABeta 1–42 at Human Amylin Receptors
pfizerpro.com; doi: 10.1210/en.2013-1658.
Joseph J. Gingell, Erica R. Burns, and Debbie L. Hay (2014) -
Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism
The Journal of Physical Chemistry; DOI: 10.1021/jp412743s.
Jason O. Matos, Greg Goldblatt, Jaekyun Jeon, Bo Chen, and Suren A. Tatulian (2014) -
Reduced Vascular Endothelial Growth Factor and Capillary Density in the Occipital Cortex in Dementia with Lewy Bodies
Brain Pathology; DOI: 10.1111/bpa.12130.
Scott Miners, Hayley Moulding, Rohan de Silva, andSeth Love (2014) -
Polyfluorinated bis-styrylbenzenes as amyloid-β plaque binding ligands
Science Direct; DOI: 10.1016/j.bmc.2014.02.054.
Rob J.A. Nabuursa, Varsha V. Kapoerchanb, Athanasios Metaxasc, Sanne de Jongha, Maaike de Backera, Mick M. Wellinga, Wim Jiskootd, Albert D. Windhorstc, Hermen S. Overkleeftb, Mark A. van Buchema, Mark Overhandb, Louise van der Weerda (2014) -
Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides
ACS Publications; DOI: 10.1021/cn400183w.
Jacques Fantini, Coralie Di Scala, Nouara Yahi, Jean-Denis Troadec, Kevin Sadelli, Henri Chahinian, and Nicolas Garmy (2014) -
Regenerating the Brain: Stem Cell Differentiation and Cholinergic Dysfunction in Alzheimer Disease
Karolinska Institutet; .
Linn Malmsten (2014) -
Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B
Biopolymers; DOI: 10.1002/bip.22470.
Saketh Chemuru, Ravindra Kodali and Ronald Wetzel (2014) -
A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain
Wiley Online Library; DOI: 10.1111/jnc.12815.
Sergey V. Matveev, Hans Peter Spielmann, Brittney M. Metts, Jing Chen, Fredrick Onono, Haining Zhu, Stephen W. Scheff, Lary C. Walker, and Harry LeVine (2014) -
A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ
Science Direct; DOI: 10.1016/j.carbpol.2014.03.060.
Peipei Wang, Wenfeng Liao, Jianping Fang, Qin Liu, Jian Yao, Minghua Hu, Kan Ding (2014) -
Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry
Clinical Chemistry; DOI: 10.1373/clinchem.2013.216515.
Thomas McAvoy, Michael E. Lassman, Daniel S. Spellman, Zhenlian Ke, Bonnie J. Howell, Oitak Wong, Lan Zhu, Michael Tanen, Arie Struyk, Omar F. Laterza (2014)