Publications
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Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease
Wiley Online Library; DOI: 10.1111/acel.12281.
Silvia Maioli, Maria Lodeiro, Paula Merino-Serrais, Farshad Falahati, Wasim Khan, Elena Puerta, Alina Codita, Roberto Rimondini, Maria J. Ramirez, Andrew Simmons, Francisco Gil-Bea, Eric Westman, Angel Cedazo-Minguez1, and for the Alzheimer's Disease Neuroimaging Initiative (2014) -
Identification and Preclinical Pharmacology of the -Secretase Modulator BMS-869780
Hindawi; http://dx.doi.org/10.1155/2014/431858.
Jeremy H. Toyn,1 Lorin A. Thompson,2 Kimberley A. Lentz,3 Jere E. Meredith Jr.,1 Catherine R. Burton,1 Sethu Sankaranararyanan,1 Valerie Guss,1 Tracey Hall,1,4 Lawrence G. Iben,1 Carol M. Krause,1 Rudy Krause,1 Xu-Alan Lin,1 Maria Pierdomenico,1 Craig Polson,1 Alan S. Robertson,1 R. Rex Denton,3 James E. Grace,3 John Morrison,3 Joseph Raybon,3 Xiaoliang Zhuo,3 Kimberly Snow,3 Ramesh Padmanabha,5 Michele Agler,5,6 Kim Esposito,5 David Harden,5 Margaret Prack,5 Sam Varma,5,7 Victoria Wong,5,8 Yingjie Zhu,5,9 Tatyana Zvyaga,5 Samuel Gerritz,2 Lawrence R. Marcin,2 Mendi A. Higgins,2 Jianliang Shi,2 Cong Wei,10,11 Joseph L. Cantone,10 Dieter M. Drexler,10 John E. Macor,2 Richard E. Olson,2 Michael K. Ahlijanian,1 and Charles F. Albright1 (2014) -
A Synchrotron-based Hydroxyl Radical Footprinting Analysis of Amyloid Fibrils and Pre-fibrillar Intermediates with Residue-specific Resolution
ACS Publications; DOI: 10.1021/bi5010409.
Alexandra L Klinger, Janna Kiselar, Serguei Alekseyevich Ilchenko, Hiroaki Komatsu, Mark R. Chance, and Paul H Axelsen (2014) -
Ultrasonic force microscopy for nanomechanical characterization of early and late-stage amyloid-β peptide aggregation
Scientific Reports; doi:10.1038/srep04004.
Claire Tinker-Mill, Jennifer Mayes, David Allsop, & Oleg V. Kolosov (2014) -
Interaction studies of luminescent conjugated oligothiophenes with aggregated Amyloid β
Diva-Portal; doi:10.1385/1-59259-890-0:571.
Alexander Sandberg (2014) -
In vitro discrimination of the role of LRP1 at the BBB cellular level: Focus on brain capillary endothelial cells and brain pericytes
Science Direct; doi:10.1016/j.brainres.2014.10.047.
Pietra Candela, Julien Saint-Pola, Marie-Christine Boucau, Fabien Gosselet, Laurence Fenart (2014) -
β-Amyloid Fibrils in Alzheimer Disease Are Not Inert When Bound to Copper Ions but Can Degrade Hydrogen Peroxide and Generate Reactive Oxygen Species
The Journal of Biological Chemistry; 10.1074/jbc.M113.525212.
Jennifer Mayes, Claire Tinker-Mill, Oleg Kolosov, Hao Zhang, Brian J. Tabner, and Daivd Allsop (2014) -
Resting microglia react to Aβ42 fibrils but do not detect oligomers or oligomer-induced neuronal damage.
Neurobiol Aging.; doi: 10.1016/j.neurobiolaging.2014.05.023.
Denise Ferrera, Nadia Mazzaro, Claudio Canale, Laura Gasparini (2014) -
Transgenic Mice Overexpressing Amyloid Precursor Protein Exhibit Early Metabolic Deficits and a Pathologically Low Leptin State Associated with Hypothalamic Dys
The Journal of Neuroscience; 10.1523/JNEUROSCI.0872-14.2014.
Makoto Ishii, Gang Wang, Gianfranco Racchumi, Jonathan P. Dyke, and Costantino Iadecola (2014) -
The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease
Science Direct; 10.1016/j.neulet.2014.04.041.
Josef Panneea, Ulrika Törnqvista, Anni Westerlunda, Martin Ingelssonb, Lars Lannfeltb, Gunnar Brinkmalma, Rita Perssona, Johan Goboma, Johan Svenssonc, Per Johanssonc, Henrik Zetterberga, Kaj Blennowa, Erik Porteliusa, (2014) -
Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I
Invest. Ophthalmol. Vis. Sci.; doi: 10.1167/iovs.13-13279.
David G. Courtney1 , Sarah D. Atkinson1,2, Johnny E. Moore1 , Eleonora Maurizi3 , Chiara Serafini3 , Graziella Pellegrini3 , Graeme C. Black4,5, Forbes D. Manson4,5, Gary H. F. Yam6 , Edwin H. Allen1 , W. H. Irwin McLean2 and C. B. Tara Moore (2014) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls
PLOS One; DOI: 10.1371/journal.pone.0088604.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2014) -
Amyloid-β Increases Metallo- and Cysteine Protease Activities in Human Macrophages
J Vasc Res.; https://doi.org/10.1159/000356334.
Castellano J., Badimon L., Llorente-Cortés V. (2014) -
Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain
Oxford Journals; doi: 10.1093/cercor/bhu105.
André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P. Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A. Valente, David Blum, Ana Maria Sebastião and Maria José Diógenes (2014) -
Molecular Mechanisms of Alzheimer′s Disease Protection by the A673T Allele of Amyloid Precursor Protein
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.589069.
Janice A. Maloney, Travis Bainbridge, Amy Gustafson, Shuo Zhang, Roxanne Kyauk, Pascal Steiner, Marcel van der Brug, Yichin Liu, James A. Ernst, Ryan J. Watts and Jasvinder K. Atwal (2014) -
Role of amyloid β in the induction of lipolysis and secretion of adipokines from human adipose tissue
Taylor Francis Online; DOI:10.4161/21623945.2014.985020.
Zhongxiao Wan, Dorrian Mah, Svetlana Simtchouk, Andreas Kluftinger & Jonathan P Little (2014) -
Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity
Science Direct; DOI: 10.1016/j.neurobiolaging.2014.03.022.
Pengcheng Hana, Zhiwei Tanga, Junxiang Yina, Marwan Maaloufa, Thomas G. Beachc, Eric M. Reimand, Jiong Shi (2014) -
Synergistic Inhibition of Synaptic Signaling in Cortical Cultures by Subcytotoxic Levels of Oligomerized Amyloid-β and Iron: Alleviation by Zinc
IOS Press; DOI: 10.3233/JAD-132696.
Marta Anne Taddeo, Sangmook Lee, Thomas B. Shea (2014) -
β-Amyloid peptides display protective activity against the human Alzheimer’s disease-associated herpes simplex virus-1
Springer Link; DOI 10.1007/s10522-014-9538-8.
Karine Bourgade, Hugo Garneau, Geneviève Giroux, Aurélie Y. Le Page, Christian Bocti, Gilles Dupuis, Eric H. Frost, Tamàs Fülöp Jr. (2014) -
Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.
Neurobiol Aging.; doi: 10.1016/j.neurobiolaging.2013.08.035.
Fernando J.Sepúlveda, Humberto Fierro, Eduardo Fernandez, Carolina Castillo, Robert W.Peoples, Carlos Opazo, Luis G.Aguayo (2014)
