Publications
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Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer’s disease
Geroscience (2023) 45 (2), 1095-1113 DOI: 10.1007/s11357-022-00708-y
Ballesteros-Álvarez, Nguyen, Sivapatham et al (2024) -
Simple, Reliable Protocol for High-Yield Solubilization of Seedless Amyloid-β Monomer
ACS Chem Neurosci (2023) 14 (1), 53-71 DOI: 10.1021/acschemneuro.2c00411
Taylor, Davis, Aubrey et al (2024) -
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells
Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease (2023) 1869 (7), 166793 DOI: 10.1016/j.bbadis.2023.166793
Piccarducci, Giacomelli, Bertilacchi et al (2024) -
The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease
Acta Neuropathol Commun (2023) 11 (1), 72 DOI: 10.1186/s40478-023-01570-5
Lau, Martinez-Valbuena, So et al (2024) -
Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
Acta Neuropathologica Communications (2023) 11 (1), 135 DOI: 10.1186/s40478-023-01633-7
Crivelli, Quadri, Vekaria et al (2024) -
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease
Mol Cell Proteomics (2023) 22 (5), 100542 DOI: 10.1016/j.mcpro.2023.100542
Hurst, Pugh, Abreha et al (2024) -
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
Cell Reports (2023) 42 (7), 112725 DOI: 10.1016/j.celrep.2023.112725
Dimou, Katsinelos, Meisl et al (2024) -
Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis
Cell Reports (2023) 42 (10), 113240 DOI: 10.1016/j.celrep.2023.113240
Wu, Du, Bimler et al (2024) -
Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
Cell Reports (2023) 42 (12), 113529 DOI: 10.1016/j.celrep.2023.113529
Krause, Kirchner, Stiller et al (2024) -
Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline
Alzheimer’s Research and Therapy (2023) 15 (1), 2 DOI: 10.1186/s13195-022-01143-z
Pascual-Lucas, Allué, Sarasa et al (2024) -
Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats
Alzheimer’s Research and Therapy (2023) 15 (1), 174 DOI: 10.1186/s13195-023-01316-4
Hector, Provost, Delignat-Lavaud et al (2024) -
Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate
Cell Death & Disease (2023) 14 (3), 192 DOI: 10.1038/s41419-023-05714-2
Grabert, Engskog-Vlachos, Škandík et al (2024) -
Single-domain antibody–based noninvasive in vivo imaging of α-synuclein or tau pathology
Science Advances (2023) 9 (19), eadf3775 DOI: 10.1126/sciadv.adf3775
Jiang, Lin, Krishnaswamy et al (2024) -
Pharmacologic inhibition of NLRP3 reduces the levels of α-synuclein and protects dopaminergic neurons in a model of Parkinson's disease
Journal of Neuroinflammation (2023) 20 (1), 147 DOI: 10.1186/s12974-023-02830-w
Amo-Aparicio, Daly, Højen et al (2024) -
Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer’s disease tau
Cell & Bioscience (2023) 13 (1), 174 DOI: 10.1186/s13578-023-01133-0
Hromadkova, Kim, Haldiman et al (2024) -
Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease
Autophagy (2023) 19 (8), 2318-2337 DOI: 10.1080/15548627.2023.2181614
Kim, Cho, Kim et al (2024) -
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration
Brain (2023) 146 (3), 1152-1165 DOI: 10.1093/brain/awac407
Gonzalez-Ortiz, Turton, Kac et al (2024) -
A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers
Journal of the American Chemical Society (2023) 145 (33), 18340-18354 DOI: 10.1021/jacs.3c03980
Khaled, Rönnbäck, Ilag et al (2024) -
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress
Molecular Neurodegeneration (2023) 18 (1), 73 DOI: 10.1186/s13024-023-00660-1
Uekawa, Hattori, Ahn et al (2024) -
Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases
Molecular Degeneration(2023) 18 (1), 29 DOI: 10.1186/s13024-023-00621-8
Sampognaro, Arya, Knudsen et al (2024)