Publications
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Capping of Aβ42 oligomers by small molecule inhibitors
ACS Publications; DOI: 10.1021/bi500910b.
Ziao Fu, Darryl S. Aucoin, Mahiuddin Ahmed, Martine Ziliox, William E. Van Nostrand, and Steven O. Smith (2014) -
Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment
ACS Publications; DOI: 10.1021/bi5001257.
Nicola Acerra, Neil M. Kad, Douglas A. Griffith, Stanislav Ott, Damian C. Crowther, and Jody M. Mason (2014) -
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
The Journal of Neuroscience; doi: 10.1523/JNEUROSCI.0410-14.2014.
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul Larkin, Ju Shi, Jenny U. Johansson, Irene Zagol-Ikapitte, Olivier Boutaud, and Katrin I. Andreasson (2014) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Daniel Paris, Ghania Ait-Ghezala, Corbin Bachmeier, Gary Laco, David Beaulieu-Abdelahad, Yong Lin, Chao Jin, Fiona Crawford and Michael Mullan (2014) -
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1..
Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0..
Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2013) -
Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays..
PLoS One; https://doi.org/10.1371/journal.pone.0114566.
Sebastian Heinzel , Maike Gold, Christian Deuschle, Felix Bernhard, Walter Maetzler, Daniela Berg, Richard Dodel (2013) -
Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases.
Science Direct; doi:10.1016/j.neulet.2014.09.041.
S.N. Pchelina, E.P. Nuzhnyib, A.K. Emelyanov,T.M. Boukina, T.S. Usenko, M.A. Nikolaev, G.N. Salogub, A.F. Yakimovskii, E.Yu. Zakharova (2013) -
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease..
Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
Min Shi, Changqin Liu, Travis J. Cook, Kristin M. Bullock, Yanchun Zhao, Carmen Ginghina, Yanfei Li, Patrick Aro, Romel Dator, Chunmei He, Michael J. Hipp, Cyrus P. Zabetian, Elaine R. Peskind, Shu-Ching Hu, Joseph F. Quinn, Douglas R. Galasko, William A. Banks, Jing Zhang (2013) -
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry.
Scientific Reports; doi:10.1038/srep05797.
John F. Kellie, Richard E. Higgs, John W. Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, & Michael D. Knierman (2013) -
The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease.
Science Direct; DOI: 10.1016/j.ejmech.2014.07.090.
Omid Tavassoly, Joe Kakish, Sergiy Nokhrin, Oleg Dmitriev, Jeremy S. Lee (2013) -
Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates.
ACS Publications; DOI: 10.1021/cn500084x.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, and Aloke K. Dutta (2013) -
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.
JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Guoxiang Liu, Jia Yu, Jinhui Ding, Chengsong Xie, Lixin Sun, Iakov Rudenko, Wang Zheng, Namratha Sastry, Jing Luo, Gay Rudow, Juan C. Troncoso, and Huaibin Cai (2013) -
Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes.
FEBS Journal; DOI: 10.1111/febs.12817 (Pay to View).
Omid Tavassoly, Sergiy Nokhrin, Oleg Y. Dmitriev, and Jeremy S. Lee (2013) -
Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells.
PLOS One; DOI: 10.1371/journal.pone.0094259.
Magdalena Gąssowska, Grzegorz A. Czapski, Beata Pająk, Magdalena Cieślik, Anna M. Lenkiewicz, Agata Adamczyk (2013) -
Resistance of naturally secreted -synuclein to proteolysis.
FEBS Journal; doi: 10.1096/fj.13-245852.
Methodios Ximerakis, Georgios Pampalakis, Theodoros I. Roumeliotis, Vasia-Samantha Sykioti, Spiros D. Garbis, Leonidas Stefanis, Georgia Sotiropoulou, and Kostas Vekrellis (2013) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls.
PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2013) -
Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Srabasti Acharya, Brian M. Safaie, Piriya Wongkongkathep, Magdalena I. Ivanova, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Gal Bitan, and Lisa J. Lapidus (2013) -
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials.
DOI 10.1007/s00401-014-1256-4; Title Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials Print ISSN 0001-6322 Online ISSN 1432-0533 Publisher Springer Berlin Heidelberg.
Markus Mandler, Elvira Valera, Edward Rockenstein, Harald Weninger, Christina Patrick, Anthony Adame, Radmila Santic, Stefanie Meindl, Benjamin Vigl, Oskar Smrzka, Achim Schneeberger, Frank Mattner, Eliezer Masliah (2013) -
Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies.
DOI: 10.1111/bpa.12130; Accepted manuscript online: 13 FEB 2014 01:41AM EST Manuscript Accepted: 2 FEB 2014.
Scott Miners, Hayley Moulding, Rohan de Silva, Seth Love (2013) -
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Neurobiology of Aging; DOI: http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.004.
Miranda E. Orr, Valentina R. Garbarino, Angelica Salinas, Rochelle Buffenstein (2013)
