Publications
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Zinc depletion regulates the processing and secretion of IL-1β
Nature.com; doi:10.1038/cddis.2013.547.
H Summersgill, H England, G Lopez-Castejon, C B Lawrence, N M Luheshi, J Pahle, P Mendes, and D Brough (2014) -
Aβ-specific DARPins as a novel class of potential therapeutics for Alzheimer’s disease
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.564013.
Nitsch Maier, Andreas Plückthun and Roger M. Claudia Späni, Rebecca Derungs, Marcel Parizek, Lisa Strobel, Susann Cattepoel, Kulic, Tobias Welt, Fabian Wirth, Petra Michael Hanenberg, Jordan McAfoose, Luka (2014) -
A novel cell line from spontaneously immortalized murine microglia
Science Direct; DOI: 10.1016/j.jneumeth.2014.05.021.
Kumi Nagamoto-Combsa, Joshua Kulasb, Colin K. Combs (2014) -
Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy
Science Direct; http://dx.doi.org/10.1016/j.bios.2013.10.060.
Francis T. Hanea, Brenda Y. Leea, Anahit Petoyanb, Arvi Raukb, Zoya Leonenko (2014) -
Is Formaldehyde the Missing Link in AD Pathology? The Differential Aggregation of Amyloid-Beta with APOE Isoforms In Vitro.
Curr Alzheimer Res.; DOI:10.2174/1567205011666140425112043.
D. Rizak, Joshua; Ma, Yuanye; Hu, Xintian (2014) -
Methylglyoxal Produced by Amyloid-β Peptide-Induced Nitrotyrosination of Triosephosphate Isomerase Triggers Neuronal Death in Alzheimer's Disease
Metapress; DOI 10.3233/JAD-131685.
Marta Tajes1, Abel Eraso-Pichot1, Fanny Rubio-Moscardó1, Biuse Guivernau1, Eva Ramos-Fernández1, Mònica Bosch-Morató1, Francesc Xavier Guix, Jordi Clarimón, Gian Pietro Miscione, Mercé Boada, Gabriel Gil-Gómez, Toshiharu Suzuki, Henrik Molina, Jordi Villà-Freixa, Rubén Vicente, Francisco J. Muñoz (2014) -
Capping of Aβ42 oligomers by small molecule inhibitors
ACS Publications; DOI: 10.1021/bi500910b.
Ziao Fu, Darryl S. Aucoin, Mahiuddin Ahmed, Martine Ziliox, William E. Van Nostrand, and Steven O. Smith (2014) -
Retro-inversal of Intracellular Selected β-Amyloid-Interacting Peptides: Implications for a Novel Alzheimer’s Disease Treatment
ACS Publications; DOI: 10.1021/bi5001257.
Nicola Acerra, Neil M. Kad, Douglas A. Griffith, Stanislav Ott, Damian C. Crowther, and Jody M. Mason (2014) -
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E2 EP4 Receptor Signaling
The Journal of Neuroscience; doi: 10.1523/JNEUROSCI.0410-14.2014.
Nathaniel S. Woodling, Qian Wang, Prachi G. Priyam, Paul Larkin, Ju Shi, Jenny U. Johansson, Irene Zagol-Ikapitte, Olivier Boutaud, and Katrin I. Andreasson (2014) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Daniel Paris, Ghania Ait-Ghezala, Corbin Bachmeier, Gary Laco, David Beaulieu-Abdelahad, Yong Lin, Chao Jin, Fiona Crawford and Michael Mullan (2014) -
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1..
Acta Neuropathol Commun.; doi: 10.1186/s40478-014-0164-0..
Scott Miners, Ruth Renfrew, Marta Swirski, Seth Love (2013) -
Naturally Occurring Alpha-Synuclein Autoantibodies in Parkinson’s Disease: Sources of (Error) Variance in Biomarker Assays..
PLoS One; https://doi.org/10.1371/journal.pone.0114566.
Sebastian Heinzel , Maike Gold, Christian Deuschle, Felix Bernhard, Walter Maetzler, Daniela Berg, Richard Dodel (2013) -
Increased plasma oligomeric alpha-synuclein in patients with lysosomal storage diseases.
Science Direct; doi:10.1016/j.neulet.2014.09.041.
S.N. Pchelina, E.P. Nuzhnyib, A.K. Emelyanov,T.M. Boukina, T.S. Usenko, M.A. Nikolaev, G.N. Salogub, A.F. Yakimovskii, E.Yu. Zakharova (2013) -
Plasma exosomal α-synuclein is likely CNS-derived and increased in Parkinson’s disease..
Acta Neurolpathol.; doi: 10.1007/s00401-014-1314-y.
Min Shi, Changqin Liu, Travis J. Cook, Kristin M. Bullock, Yanchun Zhao, Carmen Ginghina, Yanfei Li, Patrick Aro, Romel Dator, Chunmei He, Michael J. Hipp, Cyrus P. Zabetian, Elaine R. Peskind, Shu-Ching Hu, Joseph F. Quinn, Douglas R. Galasko, William A. Banks, Jing Zhang (2013) -
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry.
Scientific Reports; doi:10.1038/srep05797.
John F. Kellie, Richard E. Higgs, John W. Ryder, Anthony Major, Thomas G. Beach, Charles H. Adler, Kalpana Merchant, & Michael D. Knierman (2013) -
The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease.
Science Direct; DOI: 10.1016/j.ejmech.2014.07.090.
Omid Tavassoly, Joe Kakish, Sergiy Nokhrin, Oleg Dmitriev, Jeremy S. Lee (2013) -
Multifunctional D2/D3 Agonist D-520 with High in Vivo Efficacy: Modulator of Toxicity of Alpha-Synuclein Aggregates.
ACS Publications; DOI: 10.1021/cn500084x.
Gyan Modi, Chandrashekhar Voshavar, Sanjib Gogoi, Mrudang Shah, Tamara Antonio, Maarten E. A. Reith, and Aloke K. Dutta (2013) -
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.
JCI: The Journal of Clinical Investigation; doi:10.1172/JCI72176..
Guoxiang Liu, Jia Yu, Jinhui Ding, Chengsong Xie, Lixin Sun, Iakov Rudenko, Wang Zheng, Namratha Sastry, Jing Luo, Gay Rudow, Juan C. Troncoso, and Huaibin Cai (2013) -
Cu(II) and dopamine bind to α-Synuclein and cause large conformational changes.
FEBS Journal; DOI: 10.1111/febs.12817 (Pay to View).
Omid Tavassoly, Sergiy Nokhrin, Oleg Y. Dmitriev, and Jeremy S. Lee (2013) -
Extracellular α-Synuclein Leads to Microtubule Destabilization via GSK-3β-Dependent Tau Phosphorylation in PC12 Cells.
PLOS One; DOI: 10.1371/journal.pone.0094259.
Magdalena Gąssowska, Grzegorz A. Czapski, Beata Pająk, Magdalena Cieślik, Anna M. Lenkiewicz, Agata Adamczyk (2013)
