Publications
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Tau Monoclonal Antibody Generation based on Humanized Yeast Models: Impact on Tau Oligomerization and Diagnostics.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.627919.
Joëlle Rosseels, Jeff Van den Brande, Marie Violet, Dirk Jacobs, Pierre Grognet, Juan Lopez, Isabelle Huvent, Marina Caldara, Erwin Swinnen, Anthony Papegaey, Raphaëlle Caillierez, Valerie Buée-Scherrer, Sebastiaan Engelborghs, Guy Lippens, Morvane Colin, Luc Buée, Marie-Christine Galas, Eugeen Vanmechelen and Joris Winderickx (2013) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Daniel Paris, Ghania Ait-Ghezala, Corbin Bachmeier, Gary Laco, David Beaulieu-Abdelahad, Yong Lin, Chao Jin, Fiona Crawford and Michael Mullan (2013) -
Compounds and Compositions for use a Modulators of Tau Aggregation and Alleviation of Tauopathies.
FPO; .
Snow, Alan D.; Hu, Qubai; Lake, Thomas; Cam, Judy (2013) -
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice.
Front Aging Neurosci.; doi: 10.3389/fnagi.2014.00214.
Jean-Marie Sontag, Brandi Wasek, Goce Taleski, Josephine Smith, Erland Arning, Estelle Sontag, Teodoro Bottiglieri (2013) -
Specific binding of intravenous immunoglobulin products to tau peptide fragments.
Science Direct; doi:10.1016/j.intimp.2014.05.009.
Lynnae M. Smith, Mary P. Coffey, David A. Loeffler (2013) -
Annonacin, ein natürlicher Komplex-I Inhibitor, erhöht die Tau-Phosphorylierung im Gehirn von FTDP-17 transgenen Mäusen.
Universitat de Marburg Library; .
Gesine Respondek (2013) -
Specific binding of intravenous immunoglobulin products to tau peptide fragments.
Science Direct; http://dx.doi.org/10.1016/j.intimp.2014.05.009.
Lynnae M. Smitha, Mary P. Coffeyb, David A. Loeffler (2013) -
Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry.
Clinical Chemistry; doi: 10.1373/clinchem.2013.216515.
Thomas McAvoy, Michael E. Lassman, Daniel S. Spellman, Zhenlian Ke, Bonnie J. Howell, Oitak Wong, Lan Zhu, Michael Tanen, Arie Struyk, and Omar F. Laterza (2013) -
Alpha-Synuclein Aggregates Activate the Nlrp3Inflammasome Following Vesicle Rupture.
Loyola eCommons;. Master’s Theses. Paper 1859.
Rudy Orlando Cedillos (2012) -
Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study.
Science Direct; doi:10.1016/j.neulet.2013.12.028.
Anahit Ghochikyan, Irina Petrushina, Hayk Davtyan, Armine Hovakimyan, Tommy Saing, Arpine Davtyan, David H. Cribbs, Michael G. Agadjanyan (2012) -
In vitro Evidence that an Aqueous Extract of Centella asiatica Modulates α-Synuclein Aggregation Dynamics.
IOS Press; DOI: 10.3233/JAD-131187 (Pay to View).
Ruben Berrocal, Padmaraju Vasudevaraju, Shantinath Satappa Indi, Krothapalli Raja Surya Sambasiva Rao, and K.S. Rao (2012) -
Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro.
Elsevier B.V.; http://dx.doi.org/10.1016/j.febslet.2013.07.053 (Pay to view).
Grzegorz A. Czapski, Magdalena Gąssowska, Anna Wilkaniec, Magdalena Cieślik, and Agata Adamczyk (2012) -
Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis.
PLOS One; DOI: 10.1371/journal.pone.0062143.
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell (2012) -
Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells.
J Neurochem.; doi: 10.1111/jnc.12477.
Tamara C. Hornik, Urte Neniskyte, Guy C. BrownInf (2012) -
Capillary microsampling and analysis of 4-µl blood, plasma and serum samples to determine human α-synuclein elimination rate in mice..
Bioanalysis.; doi: 10.4155/bio.12.337.
Ove Jonsson, Ann-Charlott Steffen, Valentina Screpanti Sundquist, Juliette Janson, Stefan Martinsson, Ulrika Määttä, Anna Breitholtz Emanuelsson (2012) -
Changes in Properties of Serine 129 Phosphorylated α-Synuclein with Progression of Lewy Type Histopathology in Human Brains.
Experimental Neurology; Volume 240, February 2013, Pages 190–204; doi 10.1016/j.expneurol.2012.11.020.
Douglas G. Walker, Lue LF, Adler CH, Shill HA, Caviness JN, Sabbagh MN, Akiyama H, Serrano GE, Sue LI, Beach TG (2012) -
Critique of the use of fluorescence-based reporters in Escherichia coli as a screening tool for the identification of peptide inhibitors of Aβ42 aggregation.
J. Peptide Sci; doi: 10.1002/psc.2474 (Pay to View).
Wright, O., Zhang, L., Liu, Y., Yoshimi, T., Zheng, Y. and Tunnacliffe, A. (2012) -
Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity..
Molecular Genetics and Metabolism; 2013 Jan;108(1):56-64, ISSN 1096-7192, DOI 10.1016/j.ymgme.2012.11.010.
TL Yap, A Velayati, E Sidransky, JC Lee (2012) -
Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging.
BMC Neuroscience; doi:10.1186/1471-2202-14-148.
Astrid Gumucio, Lars Lannfelt, and Lars NG Nilsson (2012) -
Characterization of Novel CSF Tau and ptau Biomarkers for Alzheimer’s Disease.
PLoS One; DOI: 10.1371/journal.pone.0076523.
Jere E. Meredith Jr., Sethu Sankaranarayanan, Valerie Guss, Anthony J. Lanzetti, Flora Berisha, Robert J. Neely, J. Randall Slemmon, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Holly Soares, Michael Ahlijanian, Charles F. Albright (2012)