Publications
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Resistance of naturally secreted -synuclein to proteolysis.
FEBS Journal; doi: 10.1096/fj.13-245852.
Methodios Ximerakis, Georgios Pampalakis, Theodoros I. Roumeliotis, Vasia-Samantha Sykioti, Spiros D. Garbis, Leonidas Stefanis, Georgia Sotiropoulou, and Kostas Vekrellis (2013) -
Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls.
PLoS ONE; DOI: 10.1371/journal.pone.0088604.
Walter Maetzler, Anja Apel, Markus Langkamp, Christian Deuschle, Sarah Selina Dilger, Johannes Georg Stirnkorb, Claudia Schulte, Erwin Schleicher, Thomas Gasser, Daniela Berg (2013) -
Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M113.524520.
Srabasti Acharya, Brian M. Safaie, Piriya Wongkongkathep, Magdalena I. Ivanova, Aida Attar, Frank-Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Gal Bitan, and Lisa J. Lapidus (2013) -
Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials.
DOI 10.1007/s00401-014-1256-4; Title Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials Print ISSN 0001-6322 Online ISSN 1432-0533 Publisher Springer Berlin Heidelberg.
Markus Mandler, Elvira Valera, Edward Rockenstein, Harald Weninger, Christina Patrick, Anthony Adame, Radmila Santic, Stefanie Meindl, Benjamin Vigl, Oskar Smrzka, Achim Schneeberger, Frank Mattner, Eliezer Masliah (2013) -
Reduced vascular endothelial growth factor and capillary density in the occipital cortex in dementia with Lewy bodies.
DOI: 10.1111/bpa.12130; Accepted manuscript online: 13 FEB 2014 01:41AM EST Manuscript Accepted: 2 FEB 2014.
Scott Miners, Hayley Moulding, Rohan de Silva, Seth Love (2013) -
Sustained high levels of neuroprotective, high molecular weight, phosphorylated tau in the longest-lived rodent.
Neurobiology of Aging; DOI: http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.004.
Miranda E. Orr, Valentina R. Garbarino, Angelica Salinas, Rochelle Buffenstein (2013) -
Tau Monoclonal Antibody Generation based on Humanized Yeast Models: Impact on Tau Oligomerization and Diagnostics.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.627919.
Joëlle Rosseels, Jeff Van den Brande, Marie Violet, Dirk Jacobs, Pierre Grognet, Juan Lopez, Isabelle Huvent, Marina Caldara, Erwin Swinnen, Anthony Papegaey, Raphaëlle Caillierez, Valerie Buée-Scherrer, Sebastiaan Engelborghs, Guy Lippens, Morvane Colin, Luc Buée, Marie-Christine Galas, Eugeen Vanmechelen and Joris Winderickx (2013) -
The Spleen Tyrosine Kinase (syk) Regulates Alzheimer's Aβ Production and Tau Hyperphosphorylation.
The Journal of Biological Chemistry; doi: 10.1074/jbc.M114.608091.
Daniel Paris, Ghania Ait-Ghezala, Corbin Bachmeier, Gary Laco, David Beaulieu-Abdelahad, Yong Lin, Chao Jin, Fiona Crawford and Michael Mullan (2013) -
Compounds and Compositions for use a Modulators of Tau Aggregation and Alleviation of Tauopathies.
FPO; .
Snow, Alan D.; Hu, Qubai; Lake, Thomas; Cam, Judy (2013) -
Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice.
Front Aging Neurosci.; doi: 10.3389/fnagi.2014.00214.
Jean-Marie Sontag, Brandi Wasek, Goce Taleski, Josephine Smith, Erland Arning, Estelle Sontag, Teodoro Bottiglieri (2013) -
Specific binding of intravenous immunoglobulin products to tau peptide fragments.
Science Direct; doi:10.1016/j.intimp.2014.05.009.
Lynnae M. Smith, Mary P. Coffey, David A. Loeffler (2013) -
Annonacin, ein natürlicher Komplex-I Inhibitor, erhöht die Tau-Phosphorylierung im Gehirn von FTDP-17 transgenen Mäusen.
Universitat de Marburg Library; .
Gesine Respondek (2013) -
Specific binding of intravenous immunoglobulin products to tau peptide fragments.
Science Direct; http://dx.doi.org/10.1016/j.intimp.2014.05.009.
Lynnae M. Smitha, Mary P. Coffeyb, David A. Loeffler (2013) -
Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry.
Clinical Chemistry; doi: 10.1373/clinchem.2013.216515.
Thomas McAvoy, Michael E. Lassman, Daniel S. Spellman, Zhenlian Ke, Bonnie J. Howell, Oitak Wong, Lan Zhu, Michael Tanen, Arie Struyk, and Omar F. Laterza (2013) -
Alpha-Synuclein Aggregates Activate the Nlrp3Inflammasome Following Vesicle Rupture.
Loyola eCommons;. Master’s Theses. Paper 1859.
Rudy Orlando Cedillos (2012) -
Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study.
Science Direct; doi:10.1016/j.neulet.2013.12.028.
Anahit Ghochikyan, Irina Petrushina, Hayk Davtyan, Armine Hovakimyan, Tommy Saing, Arpine Davtyan, David H. Cribbs, Michael G. Agadjanyan (2012) -
In vitro Evidence that an Aqueous Extract of Centella asiatica Modulates α-Synuclein Aggregation Dynamics.
IOS Press; DOI: 10.3233/JAD-131187 (Pay to View).
Ruben Berrocal, Padmaraju Vasudevaraju, Shantinath Satappa Indi, Krothapalli Raja Surya Sambasiva Rao, and K.S. Rao (2012) -
Extracellular alpha-synuclein induces calpain-dependent overactivation of cyclin-dependent kinase 5 in vitro.
Elsevier B.V.; http://dx.doi.org/10.1016/j.febslet.2013.07.053 (Pay to view).
Grzegorz A. Czapski, Magdalena Gąssowska, Anna Wilkaniec, Magdalena Cieślik, and Agata Adamczyk (2012) -
Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis.
PLOS One; DOI: 10.1371/journal.pone.0062143.
David Freeman, Rudy Cedillos, Samantha Choyke, Zana Lukic, Kathleen McGuire, Shauna Marvin, Andrew M. Burrage, Stacey Sudholt, Ajay Rana, Christopher O'Connor, Christopher M. Wiethoff, Edward M. Campbell (2012) -
Inflammation induces multinucleation of Microglia via PKC inhibition of cytokinesis, generating highly phagocytic multinucleated giant cells.
J Neurochem.; doi: 10.1111/jnc.12477.
Tamara C. Hornik, Urte Neniskyte, Guy C. BrownInf (2012)
