Publications
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α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: relevance to human synucleopathic diseases..
Journal of Neurochemistry; 120: 440–452. 2012 Feb; doi: 10.1111/j.1471-4159.2011.07576.x.
Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. and Taglialatela, G., (2011) -
α-Synuclein potentiates interleukin-1β-induced CXCL10 expression in human A172 astrocytoma cells.
Neuroscience Letters; Volume 507, Issue 2, 24 January 2012, Pages 133–136 DOI /10.1016/j.neulet.2011.12.001.
Tousi, A.S., Buck, D.J., Curtis, T., Davis, R.L. (2011) -
A Selected Reaction Monitoring (SRM)-Based Method for Absolute Quantification of A 38, A 40, and A 42 in Cerebrospinal Fluid of Alzheimer’s Disease Patients and Healthy Controls.
IOS Press; DOI: 10.3233/JAD-2012-121471.
Josef Pannee, Erik Portelius, Madalina Oppermann, Alan Atkins, Martin Hornshaw, Ingrid Zegers, Peter Höjrup, Lennart Minthon, Oskar Hansson, Henrik Zetterberg, Kaj Blennow, Johan Gobom (2011) -
Methods for Measuring Tau Pathology in Transgenic Mouse Models.
IOS Press; DOI 10.3233/JAD-2012-121354, PMID: 22976073 (Pay to View).
Forest SK, Acker CM, d'Abramo C, Davies P. (2011) -
Development and assessment of sensitive immuno‐PCR assays for the quantification of cerebrospinal fluid three‐ and four‐repeat tau isoforms in tauopathies.
Journal of Neurochemistry; https://doi.org/10.1111/j.1471-4159.2012.07911.x.
Connie Luk, Yaroslau Compta, Nadia Magdalinou, Maria José Martí, Geshanthi Hondhamuni, Henrik Zetterberg, Kaj Blennow, Radu Constantinescu, Yolande Pijnenburg (2011) -
Constitutive secretion of tau protein by an unconventional mechanism.
Neurobiology of Disease; Available online 2 June 2012 DOI 10.1016/j.nbd.2012.05.021.
Chai, X., Dage, J.L., Citron, M. (2011) -
Sensitive quantitative assays for tau and phospho-tau in transgenic mouse models.
Neurobiology of Aging; Volume 33, Issue 8, Pages 1493-1856 (August 2012) DOI 10.1016/j.neurobiolaging.2012.05.010.
Acker, C.M., Forest, S.K., Zinkowski, R., Davies, P., d’Abramco, C. (2011) -
. United States Patent Application 20120087861;; 2012 Apr 12; DOI: y2012/0087861.html.
Human Anti-Tau Antibodies.
Nitsch, R, Chen, F , Grimm, J , Baeriswyl, J , Hock, C. (2011) -
Nanopore Analysis: An emerging technique for studying the folding and misfolding of proteins.
Prion; 2012 Apr 1;6(2):116-23. Epub 2012 Apr 1.pp 116-123 DOI /10.4161/pri.18665.
Madampage, C., Tavassoly, O., Christensen, C., Kumari, M., Lee, J.S. (2011) -
Proline Isomer-Specific Antibodies Reveal the Early Pathogenic Tau Conformation in Alzheimer's Disease.
Cell; Volume 149, Issue 1, 232-244, 2012 March 30 DOI: 10.1016/j.cell.2012.02.016.
Nakamura, K., Greenwood, A., Binder, L., Bigio, EH, Denial, S, Nicholson, L., Zhou, XZ, Lu, KP (2011) -
Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease.
The Journal of Biological Chemistry; 2012 Feb 3; The Journal of Biological Chemistry, 287, 3842-3849. doi: 10.1074/jbc.M111.277061.
Saman, S., Kim, W, Raya, M., Visnick, Y., Miro, S., Saman, S., Jackson, B., McKee, AC, Alvarez, VE, Lee, NC and Hall, GF. (2011) -
Transglutaminase 1 and its regulator tazarotene-induced gene 3 localize to neuronal tau inclusions in tauopathies.
J. Pathol.; 226: 132–142. 2012 Jan; doi: 10.1002/path.2984.
Wilhelmus, M. M., de Jager, M., Rozemuller, A. J., Brevé, J., Bol, J. G., Eckert, R. L. and Drukarch, B., (2011) -
Human Anti-Alpha-Synuclein Antibodies.
United States Patent Application; United States Patent Application 20110300077; 2011 Dec 8; DOI: y2011/0300077.html..
Weihofen, A., Grimm, J. , Nitsch, R. , Hock, C. (2010) -
The acute inflammatory response to intranigral a-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.
Journal of Neuroinflammation; 2011, 8:166.
Couch, Y, Alvarez-Erviti, L., Sibson, NR, Wood, M and Anthony, D. (2010) -
The fusogenic tilted peptide (67–78) of α-synuclein is a cholesterol binding domain.
Biochimica et Biophysica Acta (BBA) – Biomembranes; Volume 1808, Issue 10, 2011 October, Pages 2343–2351.
Fantini, J., Carlus, D., Yahi, N. (2010) -
Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein.
European Patent Application; European Patent Application EP2366714; 2011 Sept. 21.
Dodel, R., Bacher, M., Besong Agbo, D., Hagemann, S., Balzer-geldsetzer, M. (2010) -
Quantitative, Label-Free Detection of the Aggregation of α-Synuclein Using Microcantilever Arrays Operated in a Liquid Environment..
Journal of Sensors; http://dx.doi.org/10.1155/2012/874086.
Jason Jensen, Margherita Farina, Giampaolo Zuccheri, Wilfried Grange, Martin Hegner (2010) -
PPMI Parkinson’s Progression Monitoring Initiative : CSF α-synuclein interlaboratory study.
Parkinson ‘s Progession Markers Initiative; 2011 July 7 PPMI – SYN – RR-1.
Coffey C, Shaw L, Trojanowski J (2010) -
Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease.
Neurochemistry International; Volume 58, Issue 7, June 2011, Pages 785–793 DOI: 10.1016/j.neuint.2011.03.004.
Verhaara, R., Jongenelena, CA,, Gerardb, M., Baekelandt, V., Van Dama, A., Wilhelmusa, MM., Drukarcha, B. (2010) -
PAMAM G4 dendrimers affect the aggregation of α-synuclein.
International Journal of Biological Macromolecules; Volume 48, Issue 5, 2011 June 1, Pages 742–746; DOI: 10.1016/j.ijbiomac.2011.02.021..
Milowska, K., ,Malachowska, M., Gabryelak, T. (2010)
