Publications
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Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy
Cell Reports (2023) 42 (12), 113529 DOI: 10.1016/j.celrep.2023.113529
Krause, Kirchner, Stiller et al (2024) -
Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline
Alzheimer’s Research and Therapy (2023) 15 (1), 2 DOI: 10.1186/s13195-022-01143-z
Pascual-Lucas, Allué, Sarasa et al (2024) -
Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats
Alzheimer’s Research and Therapy (2023) 15 (1), 174 DOI: 10.1186/s13195-023-01316-4
Hector, Provost, Delignat-Lavaud et al (2024) -
Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate
Cell Death & Disease (2023) 14 (3), 192 DOI: 10.1038/s41419-023-05714-2
Grabert, Engskog-Vlachos, Škandík et al (2024) -
Single-domain antibody–based noninvasive in vivo imaging of α-synuclein or tau pathology
Science Advances (2023) 9 (19), eadf3775 DOI: 10.1126/sciadv.adf3775
Jiang, Lin, Krishnaswamy et al (2024) -
Pharmacologic inhibition of NLRP3 reduces the levels of α-synuclein and protects dopaminergic neurons in a model of Parkinson's disease
Journal of Neuroinflammation (2023) 20 (1), 147 DOI: 10.1186/s12974-023-02830-w
Amo-Aparicio, Daly, Højen et al (2024) -
Evolving prion-like tau conformers differentially alter postsynaptic proteins in neurons inoculated with distinct isolates of Alzheimer’s disease tau
Cell & Bioscience (2023) 13 (1), 174 DOI: 10.1186/s13578-023-01133-0
Hromadkova, Kim, Haldiman et al (2024) -
Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease
Autophagy (2023) 19 (8), 2318-2337 DOI: 10.1080/15548627.2023.2181614
Kim, Cho, Kim et al (2024) -
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type neurodegeneration
Brain (2023) 146 (3), 1152-1165 DOI: 10.1093/brain/awac407
Gonzalez-Ortiz, Turton, Kac et al (2024) -
A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers
Journal of the American Chemical Society (2023) 145 (33), 18340-18354 DOI: 10.1021/jacs.3c03980
Khaled, Rönnbäck, Ilag et al (2024) -
Border-associated macrophages promote cerebral amyloid angiopathy and cognitive impairment through vascular oxidative stress
Molecular Neurodegeneration (2023) 18 (1), 73 DOI: 10.1186/s13024-023-00660-1
Uekawa, Hattori, Ahn et al (2024) -
Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases
Molecular Degeneration(2023) 18 (1), 29 DOI: 10.1186/s13024-023-00621-8
Sampognaro, Arya, Knudsen et al (2024) -
Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
Molecular Neurodegeneration (2023) 18 (1), 61 DOI: 10.1186/s13024-023-00654-z
Upadhyay, Chhangani, Rao et al (2024) -
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Neuron (2023) 111 (15), 2383-2398.e7 DOI: 10.1016/j.neuron.2023.05.006
Sheehan, Nadarajah, Kanan et al (2024) -
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage
Nature Communications (2023) 14 (1), 1918 DOI: 10.1038/s41467-023-37561-2
Rosado-Ramos, Poças, Marques et al (2024) -
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice
Nature Communications (2023) 14 (1), 5197 DOI: 10.1038/s41467-023-40927-1
Lee, Dimitry, Song et al (2024) -
Relationship of serum beta-synuclein with blood biomarkers and brain atrophy
Alzheimers & Dementia (2023) 19 (4), 1358-1371 DOI: 10.1002/alz.12790
Oeckl, Anderl-Straub, Danek et al (2024) -
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies
Cell (2023) 186 (16), 3350-3367.e19 DOI: 10.1016/j.cell.2023.06.004
Xiang, Tao, Xia et al (2024) -
Human Microglial State Dynamics in Alzheimer’s Disease Progression
Cell; http://dx.doi.org/10.1016/j.cell.2023.08.037
Sun, Victor, Park et al (2024) -
Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease
Scientific Reports; https://doi.org/10.1186/s40478-021-01180-z
Park, J., Kam, T., Lee, S., et al. (2023)