Publications
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Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
Molecular Neurodegeneration (2023) 18 (1), 61 DOI: 10.1186/s13024-023-00654-z
Upadhyay, Chhangani, Rao et al (2024) -
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology
Neuron (2023) 111 (15), 2383-2398.e7 DOI: 10.1016/j.neuron.2023.05.006
Sheehan, Nadarajah, Kanan et al (2024) -
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage
Nature Communications (2023) 14 (1), 1918 DOI: 10.1038/s41467-023-37561-2
Rosado-Ramos, Poças, Marques et al (2024) -
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice
Nature Communications (2023) 14 (1), 5197 DOI: 10.1038/s41467-023-40927-1
Lee, Dimitry, Song et al (2024) -
Relationship of serum beta-synuclein with blood biomarkers and brain atrophy
Alzheimers & Dementia (2023) 19 (4), 1358-1371 DOI: 10.1002/alz.12790
Oeckl, Anderl-Straub, Danek et al (2024) -
Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies
Cell (2023) 186 (16), 3350-3367.e19 DOI: 10.1016/j.cell.2023.06.004
Xiang, Tao, Xia et al (2024) -
Human Microglial State Dynamics in Alzheimer’s Disease Progression
Cell; http://dx.doi.org/10.1016/j.cell.2023.08.037
Sun, Victor, Park et al (2024) -
Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease
Scientific Reports; https://doi.org/10.1186/s40478-021-01180-z
Park, J., Kam, T., Lee, S., et al. (2023) -
Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models
Journal of Neuroinflammation;doi: 10.1186/s12974-020-01980-5
Fassler, M., Rappaport, M., Cuño, C., et al. (2023) -
Imipramine and olanzapine block apoE4-catalyzed polymerization of Aβ and show evidence of improving Alzheimer’s disease cognition
bioRxiv; https://doi.org/10.1101/2021.03.28.437389
Johnson, N., Wang, A., Coughlan, C., et al. (2023) -
Heterotypic Aβ interactions facilitate amyloid assembly and modify amyloid structure
bioRxiv; https://doi.org/10.1101/2021.04.28.441786
Konstantoulea, K., Guerreiro, P., Ramakers, M., et al. (2023) -
Serotonin Promotes Serum Albumin Interaction with the Monomeric Amyloid β Peptide
International Journal of Molecular Sciences; https://doi.org/10.3390/ijms22115896
Litus, E., Kazakov, A., Deryusheva, E., et al. (2023) -
APOE2, E3 and E4 differentially modulate cellular homeostasis, cholesterol metabolism and inflammatory response in isogenic iPSC-derived astrocytes
BioRxiv; doi: 10.1016/j.stemcr.2021.11.007
Leeuw, S., Kirschner, A., Lindner, K. et al. (2022) -
The amyloid-inhibiting NCAM-PrP peptide targets Aβ peptide aggregation in membrane-mimetic environments
iScience; DOI:https://doi.org/10.1016/j.isci.2021.102852
Król, S., Österlund, N., Vosough, F., et al. (2022) -
Transcriptome analyses reveal tau isoform-driven changes in transposable element and gene expression
bioRxiv; doi.org/10.1101/2021.04.30.442101
Grundman, J., Spencer, B., Sarsoza, F., et al. (2022) -
Synthesis and evaluation of curcumin-based near-infrared fluorescent probes for the in vivo optical imaging of amyloid-β plaques
Science Direct; doi.org/10.1016/j.bioorg.2021.105167
Park, Y., Kinger, M., Min, C. et al. (2022) -
Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma
ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105237
Ojo, J., Eisenbaum, M., Shackleton, B. et al. (2022) -
Plexin-A4 mediates amyloid-β–induced tau pathology in Alzheimer’s disease animal model
ScienceDirect; https://doi.org/10.1016/j.pneurobio.2021.102075
Chung, S., Yang, J., Kim, H. et al. (2022) -
Tau-proximity ligation assay reveals extensive previously undetected pathology prior to neurofibrillary tangles in preclinical Alzheimer’s disease
Acta Neuropathologica Communications; https://doi.org/10.1186/s40478-020-01117-y
Vergniory, N., Almpani, E., Silva, A. et al. (2022) -
TDP-43–specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis
Neurology Neuroimmunology & Neuroinflammation; doi.org/10.1212/NXI.0000000000000937
Nielsen, A., Folke, J., Owczarek, S. et al. (2022)
