Publications

The PrecivityAD™ test: Accurate and reliable LC-MS/MS assays for quantifying plasma amyloid beta 40 and 42 and apolipoprotein E proteotype for the assessment of brain amyloidosis

ScienceDirect; https://doi.org/10.1016/j.cca.2021.05.011

Inhibition of aggregation of amyloid-β through covalent modification with benzylpenicillin; potential relevance to Alzheimer's disease

ScienceDirect; https://doi.org/10.1016/j.bbrep.2021.100943

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway

Front. Aging Neurosci., https://doi.org/10.3389/fnagi.2021.661505

Glucosylceramide Associated with Gaucher Disease Forms Amyloid-like Twisted Ribbon Fibrils That Induce α-Synuclein Aggregation

ACSNANO; https://doi.org/10.1021/acsnano.1c02957

Neuroprotective Effects of Trehalose and Sodium Butyrate on Preformed Fibrillar Form of α-Synuclein-Induced Rat Model of Parkinson’s Disease

American Chemical Society; doi.org/10.1021/acschemneuro.1c00144

Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology

Reporting amyloid beta levels via bioluminescence imaging with amyloid reservoirs in Alzheimer’s disease models

bioRxiv; doi.org/10.1101/2021.06.05.447217

An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β

Scientific Reports; doi.org/10.1038/s41598-021-90680-y

Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease

Cell Stem Cell; https://doi.org/10.1016/j.stem.2021.05.001

A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

Streamlined alpha-synuclein RT-QuIC assay for various biospecimens in Parkinson’s disease and dementia with Lewy bodies

Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma

ScienceDirect; https://doi.org/10.1016/j.nbd.2020.105237

Modeling the Inhibition Kinetics of Curcumin, Orange G, and Resveratrol with Amyloid-β Peptide

Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination

Cell Reports; https://doi.org/10.1016/j.celrep.2021.108835

Extract from the Marine Seaweed Padina pavonica Protects Mitochondrial Biomembranes from Damage by Amyloidogenic Peptides

Protecting P-glycoprotein at the blood–brain barrier from degradation in an Alzheimer’s disease mouse model

Oligomeric Aβ1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

Cells; https://doi.org/10.3390/cells10020413

In vitro comparison of major memory-support dietary supplements for their effectiveness in reduction/inhibition of beta-amyloid protein fibrils and tau protein tangles: key primary targets for memory loss

Scientific Reports; DOI https://doi.org/10.1038/s41598-020-79275-1

Structure-Guided Design, Synthesis, and Evaluation of 1-Indanone and 1,3-Indandione Derivatives as Ligands for Misfolded α-Synuclein Aggregates

ChemRxiv; DOI: 10.26434/chemrxiv.13817243.v1